- Ádám É, Leitgeb B, Danis J, ... Széll M. Truncating CYLD pathogenic variants in CYLD cutaneous syndrome distinctly influence CYLD proteostasis and NF-κB signaling. J Invest Dermatol. 2025 Feb 7:S0022-202X(25)00089-2. doi: 10.1016/j.jid.2024.02.042. Epub ahead of print. PMID: 39924051.
- Aiello LM, Vybornova A, Juhász S, Széll M, Bokányi E. Urban highways are barriers to social ties. Proc Natl Acad Sci U S A. 2025 Mar 11;122(10):e2408937122. doi: 10.1073/pnas.2408937122. Epub 2025 Mar 4. PMID: 40035764.
- Albert E, Biksi I, Laczkó L et al. Streptococcus hillyeri isolated from septic pleuritis in a horse. J Vet Diagn Invest. 2025 Jan 7:10406387241306724. doi: 10.1177/10406387241306724. Epub ahead of print. PMID: 39773117; PMCID: PMC11707762.
- Bajtai E, Kiss C, ... Tusnády GE et al. Therapy-induced senescence is a transient drug resistance mechanism in breast cancer. Mol Cancer. 2025 May 1;24(1):128. doi: 10.1186/s12943-025-02310-0. PMID: 40312750; PMCID: PMC12044945.
- Baksa D, Eszlari N, Torok D, Hullam G, Bagdy Gy, Juhasz G. Evening Chronotype Associates With Worse Physical and Mental Health and Headache-Related Disability Among Migraine Patients. J Sleep Res. 2025 Apr 10:e70066. doi: 10.1111/jsr.70066. Epub ahead of print. PMID: 40205879.
- Barabás Á, Erdei RJ, ... Nagy AC, Kiss OP, Takács P. Health Behavior of Young People Aged 12-18 with Autism Spectrum Disorder and Intellectual Disabilities in Hungary. Children (Basel). 2025 Jun 10;12(6):753. doi: 10.3390/children12060753. PMID: 40564711; PMCID: PMC12191208.
- Bartak BK, Nagy ZB, ... Csabai I, Sydo N, Csulak E, Merkely B, Takacs I, Molnar B. Examination of Genetic and Epigenetic Characteristics of Patients with Hyperhomocysteinemia Following High-Dose Folic Acid Consumption. Nutrients. 2025 Jun 27;17(13):2133. doi: 10.3390/nu17132133. PMID: 40647238; PMCID: PMC12251037.
- Bartha Á, Weltz B, ... Szász AM, ... Győrffy B. Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT. J Proteome Res. 2025 May 5. doi: 10.1021/acs.jproteome.4c00749. Epub ahead of print. PMID: 40322912.
- Bedőházi Z, Biricz A, Foster N, Lin YE, Csabai I. Streamlining tuberculosis detection with foundation model-based weakly supervised transformer. Comput Biol Med. 2025 Sep;195:110554. doi: 10.1016/j.compbiomed.2025.110554. Epub 2025 Jun 24. PMID: 40561575.
- Béres D, Felso R, Herczeg R, Gyenesei A, Bokor S, Molnár D. C-reactive protein and metabolic syndrome in obese and normal weight Hungarian children. Ann Nutr Metab. 2025 Mar 28:1-17. doi: 10.1159/000545201. Epub ahead of print. PMID: 40159302.
- Blondeel E, Ernst S, De Vuyst F, Diósdi Á, Pinheiro C, ... Horváth P et al. Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids. Nat Protoc. 2025 Apr 8. doi: 10.1038/s41596-025-01150-y. Epub ahead of print. PMID: 40200041.
- Bokor BA, Abdolreza A, Kaptás F, Pál M, Battyani Z, Széll M, Nagy N. Novel Variants in Medium and Low Penetrance Predisposing Genes in a Hungarian Malignant Melanoma Cohort With Increased Risk. Pigment Cell Melanoma Res. 2025 Jan;38(1):e13214. doi: 10.1111/pcmr.13214. Epub 2024 Nov 28. PMID: 39609110.
- Buzgó L, Kiss Z, Göbhardter D, Laczkó L, Damjanova I, Kardos G, Tóth Á. High Prevalence of Cefiderocol Resistance Among New Delhi Metallo-β-Lactamase Producing Klebsiella pneumoniae High-Risk Clones in Hungary. Antibiotics (Basel). 2025 May 8;14(5):475. doi: 10.3390/antibiotics14050475. PMID: 40426541; PMCID: PMC12108422.
- Bűdi L, Hammer D, Varga R, Müller V, Tárnoki ÁD, Tárnoki DL, Mészáros M, Bikov A, Horváth P. Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer. Pathol Oncol Res. 2025 Jan 6;30:1611929. doi: 10.3389/pore.2024.1611929. PMID: 39835329; PMCID: PMC11742942.
- Callari M, Dugo M, Barreca M, Győrffy B et al. Determinants of response and molecular dynamics in HER2+ER+ breast cancers from the NA-PHER2 trial receiving HER2- targeted and endocrine therapies. Nat Commun. 2025 Mar 4;16(1):2195. doi: 10.1038/s41467-025-57293-9. PMID: 40038334; PMCID: PMC11880565.
- Caruso A, Accattatis FM, ... Győrffy B et al. Adipocyte/Tumor cell crosstalk via IGF-1/TXNIP axis promotes malignancy and endocrine resistance in breast cancer. Cell Commun Signal. 2025 Jun 3;23(1):262. doi: 10.1186/s12964-025-02262-4. PMID: 40462107; PMCID: PMC12135404.
- Csatári-Kovács R, Röszer T, Csősz É. Comparative Analysis of Omega-3, Omega-6, and Endocannabinoid Content of Human, Cattle, Goat, and Formula Milk. Foods. 2025 May 17;14(10):1786. doi: 10.3390/foods14101786. PMID: 40428565; PMCID: PMC12110994.
- Darida M, Rubovszky G, ... Kenessey I, Wéber A et al. Improvement in breast cancer survival across molecular subtypes in Hungary between 2011 and 2020: a nationwide, retrospective study. Front Oncol. 2025 Mar 31;15:1465511. doi: 10.3389/fonc.2025.1465511. PMID: 40231260; PMCID: PMC11994442.
- Diosdi A, Piccinini F, ... Horváth P, Harmati M. Single-cell light-sheet fluorescence 3D images of tumour-stroma spheroid multicultures. Sci Data. 2025 Mar 24;12(1):492. doi: 10.1038/s41597-025-04832-0. PMID: 40128531; PMCID: PMC11933373.
- Dobra G, Gyukity-Sebestyen E, … Széll M, Buzas K. Proteomic profiling of serum small extracellular vesicles predicts post-COVID syndrome development. Clin Immunol. 2025 May 24:110532. doi: 10.1016/j.clim.2025.110532. Epub ahead of print. PMID: 40419011.
- Dobson L, Tusnády GE, Tompa P. Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications. Brief Bioinform. 2025 Mar 4;26(2):bbaf104. doi: 10.1093/bib/bbaf104. PMID: 40067116; PMCID: PMC11894802.
- Erdelyi-Hamza B, Torok D, ... Bagdy Gy, Juhasz G, Gonda X. Disentangling nature and nurture: Exploring the genetic background of depressive symptoms in the absence of recent stress exposure using a GWAS approach. J Affect Disord. 2025 Nov 1;388:119731. doi: 10.1016/j.jad.2025.119731. Epub 2025 Jun 18. PMID: 40541832.
- Erdős G, Deutsch N, Dosztányi Zs. AIUPred - Binding: Energy Embedding to Identify Disordered Binding Regions. J Mol Biol. 2025 Mar 5:169071. doi: 10.1016/j.jmb.2025.169071. Epub ahead of print. PMID: 40133781.
- Faludi Vargáné E, Ghanem AS, Nguyen CM, Pataki J, Szőllősi GJ, Nagy AC. Influencing factors on attendance in cervical cancer screening among women with diabetes in Hungary: a cross-sectional study using European Health Interview Surveys 2009-2019. Front Oncol. 2025 Apr 29;15:1501654. doi: 10.3389/fonc.2025.1501654. PMID: 40365342; PMCID: PMC12069032.
- Fekete JT, Győrffy B. MetaAnalysisOnline.com: Web-Based Tool for the Rapid Meta-Analysis of Clinical and Epidemiological Studies. J Med Internet Res. 2025 Mar 6;27:e64016. doi: 10.2196/64016. PMID: 39928123; PMCID: PMC11926438.
- Fekete M, Varga P, Ungvari Z, Fekete JT, ... Menyhart O, ... Győrffy B. The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer's disease: a meta-analysis. Geroscience. 2025 Jan 11. doi: 10.1007/s11357-024-01488-3. Epub ahead of print. PMID: 39797935.
- Fekete R, Simats A, Bíró E, ... Csikász-Nagy A et al. Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6- related systemic inflammation in COVID-19. Nat Neurosci. 2025 Mar 6. doi: 10.1038/s41593-025-01871-z. Epub ahead of print. PMID: 40050441.
- Fekete Z, Német Z, Ninausz N, Fehér P, Schiller M, ... Barta E. Whole-Genome Sequencing-Based Population Genetic Analysis of Wild and Domestic Rabbit Breeds. Animals (Basel). 2025 Mar 9;15(6):775. doi: 10.3390/ani15060775. PMID: 40150307; PMCID: PMC11939179.
- Ferenczi K, Nagy ZF, Istenes I, Eid H, Bödör Cs, Timár B, Demeter J. Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A. Pathol Oncol Res. 2025 May 21;31:1612108. doi: 10.3389/pore.2025.1612108. PMID: 40469412; PMCID: PMC12134567.
- Fichó E, Pancsa R, Magyar C, ... Tusnády GE. MFIB 2.0: a major update of the database of protein complexes formed by mutual folding of the constituting protein chains. Nucleic Acids Res. 2025 Jan 6;53(D1):D487-D494. doi: 10.1093/nar/gkae976. PMID: 39526403; PMCID: PMC11701542.
- Forró B, Kajtár B, ... Gyenesei A, Kosztolányi S, Kehl D, Jáksó P. Multiparameter flow cytometric and transcriptional analyis of CD20 positive T-cells in bone marrow in patients of multiple myeloma and monoclonal gammopathy of undetermined significance. Front Immunol. 2025 Feb 26;16:1464940. doi: 10.3389/fimmu.2025.1464940. PMID: 40079005; PMCID: PMC11896981.
- Ghanem AS, Bata R, Kovács N, Nagy AC. Sociodemographic inequalities in the global burden trends and machine learning-based projections of periodontitis from 1990 to 2030 across different development levels. Front Oral Health. 2025 Jun 17;6:1609961. doi: 10.3389/froh.2025.1609961. PMID: 40599686; PMCID: PMC12209297.
- Ghanem AS, Faludi EV, Bata R, ... Nagy AC. Cancer prevalence and its determinants in Hungary: Analyzing data from the 2009, 2014, and 2019 European Health Interview Surveys. PLoS One. 2025 Feb 13;20(2):e0315689. doi: 10.1371/journal.pone.0315689. PMID: 39946492; PMCID: PMC11825095.
- Ghanem AS, Móré M, Nagy AC. Analysis of Molecular Aspects of Periodontitis as a Risk Factor for Neurodegenerative Diseases: A Single-Center 10-Year Retrospective Cohort Study. Int J Mol Sci. 2025 Mar 7;26(6):2382. doi: 10.3390/ijms26062382. PMID: 40141026; PMCID: PMC11941802.
- Ghanem AS, Sipos K, Tóth Á, Nagy AC. Inflammatory Biomarkers and Oral Health Disorders as Predictors of Head and Neck Cancer: A Retrospective Longitudinal Study. Int J Mol Sci. 2025 Mar 4;26(5):2279. doi: 10.3390/ijms26052279. PMID: 40076898; PMCID: PMC11900271.
- Ghanem AS, Tóth Á, Nagy AC. Socio-demographic disparities in global trends of lip and oral cavity neoplasms from 1990 to 2021. Sci Rep. 2025 Feb 4;15(1):4230. doi: 10.1038/s41598-025-88684-z. PMID: 39905081; PMCID: PMC11794761.
- Ghanem AS, Tóth Á, Takács P, Ulambayar B, Móré M, Nagy AC. Flexible Parametric Survival Modeling of Transaminases as Predictive Biomarkers for Non- Alcoholic Fatty Liver Disease: A Retrospective Longitudinal Study (2012-2022). Int J Mol Sci. 2025 May 24;26(11):5057. doi: 10.3390/ijms26115057. PMID: 40507868; PMCID: PMC12153985.
- Ghanem AS, Trefan L, Márton I, Fadgyas-Freyler P, Nagy AC, Móré M. Oral cancer in Hungary: An epidemiological profile (2015-2019). PLoS One. 2025 Jul 3;20(7):e0327566. doi: 10.1371/journal.pone.0327566. PMID: 40608739; PMCID: PMC12225832.
- Gubán R, Parrag P, Kispál MT, Czirbesz K, Danyi T, Kenessey I, Liszkay G. Characterization of Melanoma in Hungary Based on a Retrospective Single-Center Study Between 2001 and 2018. Cancers (Basel). 2025 Jun 27;17(13):2171. doi: 10.3390/cancers17132171. PMID: 40647468; PMCID: PMC12249122.
- Guedes J, Szadai L, ... Szász AM, Vereb Z et al. The melanoma MEGA-study: Integrating proteogenomics, digital pathology, and AI-analytics for precision oncology. J Proteomics. 2025 Aug 15;319:105482. doi: 10.1016/j.jprot.2025.105482. Epub 2025 Jun 16. PMID: 40532957.
- Guedes J, Woldmar N, Szász AM, Wieslander E, Pawłowski K, et.al. A perspective on integrating digital pathology, proteomics, clinical data and AI analytics in cancer research. J Proteomics. 2025 Jul 16;320:105493. doi: 10.1016/j.jprot.2025.105493. Epub ahead of print. PMID: 40680990.
- Hegedüs B, Sahu N, ... Gyenesei A, Freitag M, Grigoriev IV, Nagy LG. Morphogenesis, starvation, and light responses in a mushroom-forming fungus revealed by long-read sequencing and extensive expression profiling. Cell Genom. 2025 Apr 17:100853. doi: 10.1016/j.xgen.2025.100853. Epub ahead of print. PMID: 40262612.
- Horváth P, Coscia F. Spatial proteomics in translational and clinical research. Mol Syst Biol. 2025 Apr 14. doi: 10.1038/s44320-025-00101-9. Epub ahead of print. PMID: 40229558.
- Jablonszky M, Laczi M, Nagy G, Tóth Z, Zsebők S, Garamszegi LZ. Close Males Sing With Dissimilar Minimum Frequency and Repertoire Size in a Wild Passerine. Ecol Evol. 2025 Apr 15;15(4):e71044. doi: 10.1002/ece3.71044. PMID: 40235729; PMCID: PMC11997371.
- Jorda A, Ensle D, Eser H, Glötzl F, Riedl B, Széll M et al. Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir in non-hospitalized adults with COVID-19: a population-based, retrospective cohort study. Clin Microbiol Infect. 2025 Mar;31(3):451-458. doi: 10.1016/j.cmi.2024.10.026. Epub 2024 Nov 4. PMID: 39505067.
- Jordán S, Laczkó L, Póliska S, Korompai T, Sramkó G. The mitochondrial genome of the steppe carpenter moth (Paracossulus thrips Hübner, 1818): Structural analysis and phylogenetic implications. Sci Rep. 2025 Mar 11;15(1):8393. doi: 10.1038/s41598-025-93646-6. PMID: 40069326; PMCID: PMC11897335.
- Kárteszi J, Nagy N, Széll M et al. Timely recognition of a probably life-threatening genodermatosis: familial case report of hereditary leiomyomatosis and renal cell cancer. Pathol Oncol Res. 2025 Apr 8;31:1612086. doi: 10.3389/pore.2025.1612086. PMID: 40264827; PMCID: PMC12011599.
- Kaya F, Bewicke-Copley F, ... Bödör Cs et al. DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes. Leukemia. 2025 Apr 9. doi: 10.1038/s41375-025-02593-8. Epub ahead of print. PMID: 40204893.
- Keller J, Danis J, ... Széll M et al. LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes. Cell Death Dis. 2025 Mar 22;16(1):198. doi: 10.1038/s41419-025-07537-9. PMID: 40121229; PMCID: PMC11929817.
- Kenéz B, Koplányi G, Decsi B, Molnár Z, Horváth P, Katona G, Balogh GT, Balogh-Weiser D. Development of a Novel Human Serum Albumin-Based Tool for Effective Drug Discovery: The Investigation of Protein Quality and Immobilization. J Med Chem. 2025 Jan 15. doi: 10.1021/acs.jmedchem.4c02136. Epub ahead of print. PMID: 39813641.
- Kilim O, Olar A, Biricz A, Madaras L, Pollner P, Szállási Z, Sztupinszki Z, Csabai I. Histopathology and proteomics are synergistic for high-grade serous ovarian cancer platinum response prediction. NPJ Precis Oncol. 2025 Jan 26;9(1):27. doi: 10.1038/s41698-025-00808-w. PMID: 39863682; PMCID: PMC11762732.
- Kim Y, Doma V, … Szász AM et al. Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies. Cancer. 2025 Jul 1;131(13):e35897. doi: 10.1002/cncr.35897. PMID: 40545870; PMCID: PMC12183497.
- Kiss Z, Berki TL, ... Kenessey I et al. Overall Survival of Hungarian Cancer Patients Diagnosed Between 2011 and 2019, Based on the Health Insurance Fund Database. Cancers (Basel). 2025 May 15;17(10):1670. doi: 10.3390/cancers17101670. PMID: 40427166; PMCID: PMC12110003.
- Kiss Z, Maráz A, ... Kenessey I et al. Improvements in cancer survival in Hungary: a nationwide epidemiology study between 2011-2019 based on a health insurance fund database. Front Oncol. 2025 Apr 3;15:1446611. doi: 10.3389/fonc.2025.1446611. PMID: 40248209; PMCID: PMC12004281.
- Kleiner D, Haghverdi F, ... Monostory K et al. How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions. Eur J Hosp Pharm. 2025 Jul 8:ejhpharm-2025-004478. doi: 10.1136/ejhpharm-2025-004478. Epub ahead of print. PMID: 40628495.
- Kovács KA, Kerepesi C, ... Szász AM, Kulka J, Tőkés AM. Machine learning prediction of breast cancer local recurrence localization, and distant metastasis after local recurrences. Sci Rep. 2025 Feb 10;15(1):4868. doi: 10.1038/s41598-025-89339-9. PMID: 39929942; PMCID: PMC11811162.
- Kovács SA, Kovács T, ... Fekete JT, Győrffy B. Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti-PD1 resistance in skin cutaneous melanoma. Br J Pharmacol. 2025 May 5. doi: 10.1111/bph.70052. Epub ahead of print. PMID: 40324810.
- Krause S, Torok D, Bagdy Gy, Juhasz G, Gonda X. Genome-wide by trait interaction analyses with neuroticism reveal chronic pain-associated depression as a distinct genetic subtype. Transl Psychiatry. 2025 Mar 29;15(1):108. doi: 10.1038/s41398-025-03331-5. PMID: 40157903; PMCID: PMC11954882.
- Krenhardt K, Jablonszky M, Barta KA, Laczi M, Nagy G, Zsebők S, Garamszegi LZ. Birdsong as an Indicator of Habitat Structure and Quality. Ecol Evol. 2025 Jun 4;15(6):e71510. doi: 10.1002/ece3.71510. PMID: 40475870; PMCID: PMC12137194.
- Krishnan SV, Anaswara PA, ... Miklós I, Király S, Pócsi I, Pusztahelyi T. Unveiling the Perspective on Weissella confusa as a Promising Biocontrol Agent Against Fusaria. Microorganisms. 2025 Mar 15;13(3):666. doi: 10.3390/microorganisms13030666. PMID: 40142558; PMCID: PMC11944590.
- Kuras M, Betancourt LH, Hong R, ... Szász AM et al. Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma. Cancers (Basel). 2025 Feb 27;17(5):832. doi: 10.3390/cancers17050832. PMID: 40075679; PMCID: PMC11899103.
- Laczkó L, Nagy NA, Nagy Á, Maroda Á, Sály P. An updated reference genome of Barbatula barbatula (Linnaeus, 1758). Sci Data. 2025 Jan 22;12(1):137. doi: 10.1038/s41597-025-04469-z. PMID: 39843539; PMCID: PMC11754907.
- Lan A, Torok D, Einat H, Bagdy Gy, Juhasz G, Gonda X. Chronotypes are significantly associated with emotional well-being in a general population cohort in Hungary. Sci Rep. 2025 May 8;15(1):16054. doi: 10.1038/s41598-025-00893-8. PMID: 40341219; PMCID: PMC12062299.
- László T, Pinczés LI, Bátai B, Varga L, ... Bödör Cs. Resistance mechanisms and clonal dynamics in mantle cell lymphoma treated with sequential BTKi and venetoclax therapy. J Pathol. 2025 May 15. doi: 10.1002/path.6434. Epub ahead of print. PMID: 40371810.
- Lehoczki A, Menyhart O, Andrikovics H, Fekete M, Kiss C, Mikala G, Ungvari Z, Győrffy B. Prognostic impact of a senescence gene signature in multiple myeloma. Geroscience. 2025 Mar 25. doi: 10.1007/s11357-025-01622-9. Epub ahead of print. PMID: 40133591.
- Lonardi A, Széll M, De Bacco C. Cohesive urban bicycle infrastructure design through optimal transport routing in multilayer networks. J R Soc Interface. 2025 Feb;22(223):20240532. doi: 10.1098/rsif.2024.0532. Epub 2025 Feb 5. PMID:39904366; PMCID: PMC11793972.
- Mahdi M, Kiarie IW, Mótyán JA, Hoffka G, Al-Muffti AS, Tóth A, Tőzsér J. Receptor Binding for the Entry Mechanisms of SARS-CoV-2: Insights from the Original Strain and Emerging Variants. Viruses. 2025 May 10;17(5):691. doi: 10.3390/v17050691. PMID: 40431702; PMCID: PMC12115909.
- Major E, Lin KH, Lee SC, Káldi K, Győrffy B, Tigyi GJ, Benyó Z. LPA suppresses HLA-DR expression in human melanoma cells: a potential immune escape mechanism involving LPAR1 and DR6-mediated release of IL-10. Acta Pharmacol Sin. 2025 Jan;46(1):222-230. doi: 10.1038/s41401-024-01373-x. Epub 2024 Aug 26. PMID: 39187677; PMCID: PMC11696067.
- Meinhardt G, Waldhäusl H, ... Than NG et al. The multifaceted roles of the transcriptional coactivator TAZ in extravillous trophoblast development of the human placenta. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2426385122. doi: 10.1073/pnas.2426385122. Epub 2025 Apr 14. PMID: 40228123; PMCID: PMC12037006.
- Menyhart O, Győrffy B. Multiplicity corrections in life sciences: challenges and consequences. Int J Epidemiol. 2025 Jun 11;54(4):dyaf098. doi: 10.1093/ije/dyaf098. PMID: 40579911; PMCID: PMC12205177.
- Menyhart O, Kothalawala WJ, Győrffy B. A gene set enrichment analysis for cancer hallmarks. J Pharm Anal. 2025 May;15(5):101065. doi: 10.1016/j.jpha.2024.101065. Epub 2024 Aug 3. PMID: 40496069; PMCID: PMC12151186.
- Mester B, Lipták Z, ... Bödör Cs, Kovács A, Merkely B, Szűcs A. Inherited Hypertrabeculation? Genetic and Clinical Insights in Blood Relatives of Genetically Affected Left Ventricular Excessive Trabeculation Patients. Life (Basel). 2025 Jan 22;15(2):150. doi: 10.3390/life15020150. PMID: 40003559; PMCID: PMC11856360.
- Meyer EH, Pavlova A, ... Miklós D, Rezvani A, Shiraz P, Sidana S, Shizuru J, Weng WK, Agrawal V, Putnam A, Fernhoff N, Tamarisis J, Lu Y, Pawar RD, McClellan JS, Lowsky R, Negrin RS. Donor regulatory T-cell therapy to prevent graft-versus-host disease. Blood. 2025 May 1;145(18):2012-2024. doi: 10.1182/blood.2024026446. PMID: 39792934.
- Mótyán JA, Nagy T, Nagyné Veres Á, Golda M, Mahdi M, Tőzsér J. Identification of SARS-CoV-2 Main Protease Cleavage Sites in Bovine β-Casein. Int J Mol Sci. 2025 Jun 18;26(12):5829. doi: 10.3390/ijms26125829. PMID: 40565292; PMCID: PMC12192567.
- Mótyán JA, Veres ÁN, Tőzsér J. Characterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase. Proteins. 2025 May;93(5):1054-1066. doi: 10.1002/prot.26794. Epub 2025 Jan 2. PMID: 39748618; PMCID: PMC11968563.
- Munkácsy Gy, Santarpia L, Győrffy B. Exploring immune activation patterns in HER2-low and HER2-ultralow breast cancer subtypes. Oncologist. 2025 Jun 4;30(6):oyaf081. doi: 10.1093/oncolo/oyaf081. PMID: 40549048; PMCID: PMC12205994.
- Murányi M, Domoszlai A, Nagy AC, Flaskó T. Comparing functional outcomes of glansectomy with or without glans reconstruction. Can J Urol. 2025 Apr 30;32(2):119-127. doi: 10.32604/cju.2025.063821. PMID: 40331261.
- Müller D, Győrffy B. EpigenPlot: An interactive web platform for DNA methylation-based biomarker and drug target discovery in colorectal cancer. Br J Pharmacol. 2025 Apr;182(7):1452-1465. doi: 10.1111/bph.17455. Epub 2025 Jan 27. PMID: 39871596.
- Nagy N, Abdolreza A, Pál M, ... Széll M. Oculocutaneous albinism type 1B associated with allelic combination of a risk haplotype. J Dermatol Sci. 2025 Apr 17:S0923-1811(25)00061-1. doi: 10.1016/j.jdermsci.2025.04.007. Epub ahead of print. PMID: 40307117.
- Nagy N, Szalenko-Tőkés Á, ... Széll M. Novel Pathogenic Variant of the TRRAP Gene Detected in a Hungarian Family with Autosomal Dominant Non-Syndromic Hearing Loss. Int J Mol Sci. 2025 Feb 13;26(4):1583. doi: 10.3390/ijms26041583. PMID: 40004049; PMCID: PMC11855266.
- Nagy SÁ, Csabai I, Varga T, Póth-Szebenyi B, Gábor G, Solymosi N. Neural Network-Aided Milk Somatic Cell Count Increase Prediction. Vet Sci. 2025 Apr 29;12(5):420. doi: 10.3390/vetsci12050420. PMID: 40431513; PMCID: PMC12115723.
- Németh A, Gecse K, … Bagdy Gy, Juhász G. Hypothalamic connectivity strength is decreasing with polygenic risk in migraine without aura patients. Eur J Pharm Sci. 2025 Jul 1;210:107123. doi: 10.1016/j.ejps.2025.107123. Epub 2025 May 10. PMID: 40354987.
- Németh K, Mezei E, Vörös J, Borka K, Pesti A, Kenessey I, Kiss A, Budai A. Subtype-associated complexity and prognostic significance of the NLRP3 inflammasome landscape in pancreatic neoplasms. J Pathol Clin Res. 2025 Mar;11(2):e70019. doi: 10.1002/2056-4538.70019. PMID: 39969214; PMCID: PMC11837281.
- Nieto-Jiménez C, Garcia-Lorenzo E, ... Munkácsy Gy, Győrffy B et al. In silico evaluation of the immunogenic profile of lung cancers with SMARCA4 genetic alterations. Sci Rep. 2025 May 22;15(1):17832. doi: 10.1038/s41598-025-02494-x. PMID: 40404793; PMCID: PMC12098669.
- Novák J, Takács T, ... Than NG, Buday L, Balogh A, Vas V. The sweet and the bitter sides of galectin-1 in immunity: its role in immune cell functions, apoptosis, and immunotherapies for cancer with a focus on T cells. Semin Immunopathol. 2025 Apr 3;47(1):24. doi: 10.1007/s00281-025-01047-8. PMID: 40178639; PMCID: PMC11968517.
- Ocana A, Pandiella A, Privat C, Bravo I, Luengo-Oroz M, Amir E, Győrffy B. Integrating artificial intelligence in drug discovery and early drug development: a transformative approach. Biomark Res. 2025 Mar 14;13(1):45. doi:10.1186/s40364-025-00758-2. PMID: 40087789; PMCID: PMC11909971.
- Oskolas H, Nogueira FCN, ... Szász AM et al. Comprehensive biobanking strategy with clinical impact at the European Cancer Moonshot Lund Center. J Proteomics. 2025 May 30;316:105442. doi: 10.1016/j.jprot.2025.105442. Epub 2025 Apr 15. PMID: 40246065.
- Péterffy B, Krizsán S, ... Bödör Cs, Alpár D. MOLECULAR PROFILING REVEALS NOVEL GENE FUSIONS AND GENETIC MARKERS FOR REFINED PATIENT STRATIFICATION IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA. Mod Pathol. 2025 Feb 24:100741. doi: 10.1016/j.modpat.2025.100741. Epub ahead of print. PMID: 40010436.
- Pla I, Szabolcs BL, ... Bartha Á, ... Győrffy B, Szász AM et al. Unbiased Drug Target Prediction Reveals Sensitivity to Ferroptosis Inducers, HDAC and RTK Inhibitors in Melanoma Subtypes. Int J Dermatol. 2025 May;64(5):870-881. doi: 10.1111/ijd.17586. Epub 2024 Dec 25. PMID: 39722169; PMCID: PMC12008611.
- Polcz P, Reguly IZ, ... Pongor S, Csikász-Nagy A, Szederkényi G. Smart epidemic control: A hybrid model blending ODEs and agent-based simulations for optimal, real-world intervention planning. PLoS Comput Biol. 2025 May 8;21(5):e1013028. doi: 10.1371/journal.pcbi.1013028. PMID: 40338990; PMCID: PMC12061170.
- Raab M, Gasimli K, Győrffy B, Peña-Llopis S, Becker S, Sanhaji M, Strebhardt K. Truncated DAPK Variants Restore Tumor Suppressor Activity and Synergize with Standard Therapies in High-Grade Serous Ovarian Cancer. Cancers (Basel). 2025 Jun 8;17(12):1910. doi: 10.3390/cancers17121910. PMID: 40563561; PMCID: PMC12190691.
- Raab M, Győrffy B, Peña-Llopis S, Fietz D et al. Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high-grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in preclinical models. Cancer Commun (Lond). 2025 May 20. doi: 10.1002/cac2.70029. Epub ahead of print. PMID: 40391786.
- Salman ND, Hanker LC, Győrffy B, Bartha Á, Proppe L, Götte M. The Prognostic Value of the Hedgehog Signaling Pathway in Ovarian Cancer. Int J Mol Sci. 2025 Jun 19;26(12):5888. doi: 10.3390/ijms26125888. PMID: 40565349; PMCID: PMC12193027.
- Sawada Y, Kikugawa T, … Győrffy B et al. CTHRC1 promotes bone metastasis in prostate cancer. Int J Cancer. 2025 Jun 21. doi: 10.1002/ijc.70012. Epub ahead of print. PMID: 40542593.
- Simon B, Köteles I, Kovács R, Kraszni M, Horváth P, Hosztafi S, Mazák K. Synthesis and physicochemical characterization of new potential haptens and their precursors with morphine skeleton. Eur J Pharm Sci. 2025 Jun 1;209:107089. doi: 10.1016/j.ejps.2025.107089. Epub 2025 Mar 31. PMID: 40174659.
- Sipos K, Márton I, Móré M, Nagy AC, Kiss C. Assessing the factors affecting the accessibility of primary dental care for people with haemophilia. Haemophilia. 2025 Jan;31(1):69-77. doi: 10.1111/hae.15124. Epub 2024 Nov 27. PMID: 39604148; PMCID: PMC11780182.
- Sipos K, Márton I, Móré M, Nagy AC, Kiss C. The attitudes and treatment practices of Hungarian primary care dentists regarding dental care for patients with haemophilia. Sci Rep. 2025 Jul 19;15(1):26261. doi: 10.1038/s41598-025-11818-w. PMID: 40684000; PMCID: PMC12276225.
- Smith CJ, Goyal A, ... Miklós D, Bharadwaj S. Lisocabtagene Maraleucel for Richter's Transformation-A Case Series. EJHaem. 2025 Mar 10;6(2):e270011. doi: 10.1002/jha2.70011. PMID: 40066130; PMCID: PMC11891774.
- Solymosi N, Tóth AG, Nagy SÁ, Csabai I, Feczkó C, Reibling T, Németh T. Clinical considerations on antimicrobial resistance potential of complex microbiological samples. PeerJ. 2025 Jan 28;13:e18802. doi: 10.7717/peerj.18802. PMID: 39897495; PMCID: PMC11784533.
- Széles A, Schöll K, Hirka G, Monostory K, Renkecz T. Toxicokinetic Characterization of Isopropyl Glycidyl Ether in Rat by a Validated LC-APCI-MS/MS Method Using In-Source Derivatization. Chem Res Toxicol. 2025 Mar 17;38(3):380-391. doi: 10.1021/acs.chemrestox.4c00376. Epub 2025 Mar 4. PMID: 40040238.
- Szentivanyi T, V González L, Klein Á, Soltész Z, Garamszegi LZ. Complementing community science with xenomonitoring: Understanding the eco-epidemiology of Dirofilaria immitis infection in dogs and mosquitoes. Parasit Vectors. 2025 Jun 20;18(1):233. doi: 10.1186/s13071-025-06882-0. PMID: 40542375; PMCID: PMC12181931.
- Szojka ZI, Kunkli B, … Tőzsér J, Mahdi M. Transcriptomic Analysis Reveals Key Pathways Influenced by HIV-2 Vpx. Int J Mol Sci. 2025 Apr 8;26(8):3460. doi: 10.3390/ijms26083460. PMID: 40331967; PMCID: PMC12026760.
- Sztupinszki Z, Fiam R, Pipek O, Diossy M, Börcsök J, Prosz A, Csabai I, Szallasi Z. Polymerase theta expression is correlated with proliferative capacity but not with DNA repair deficiency status in solid tumors. NPJ Precis Oncol. 2025 Jun 20;9(1):200. doi: 10.1038/s41698-025-01000-w. PMID: 40542116; PMCID: PMC12181433.
- Teszak T, Barcziova T, Bödör Cs et al. Donor-Derived Cell-Free DNA Versus Left Ventricular Longitudinal Strain and Strain-Derived Myocardial Work Indices for Identification of Heart Transplant Injury. Biomedicines. 2025 Apr 1;13(4):841. doi: 10.3390/biomedicines13040841. PMID: 40299413; PMCID: PMC12025175.
- Torok D, Hegedus K, Varga H, Gonda X, Bagdy Gy, Petschner P. Neuroinflammation and Mood: Dissecting the Role of Eotaxin-1 in Depression. Neuropsychopharmacol Hung. 2025 Jun;27(2):115-120. English. PMID: 40608294.
- Tóth AG, Solymosi N, Tenk M, Káldy Z, Németh T. First Animal Source Metagenome Assembly of Lawsonella clevelandensis from Canine External Otitis. Pathogens. 2025 May 10;14(5):465. doi: 10.3390/pathogens14050465. PMID: 40430785; PMCID: PMC12114289.
- Tóth AG, Tóth DL, Remport L, Tóth I, ... Solymosi N. A One Health Approach Metagenomic Study on Antimicrobial Resistance Traits of Canine Saliva. Antibiotics (Basel). 2025 Apr 25;14(5):433. doi: 10.3390/antibiotics14050433. PMID: 40426500; PMCID: PMC12108403.
- Tóth BB, Hegedűs G, Virág E, Pethő GT, Laczkó L, Fésüs L. In silico analysis of UCP promoters predicts conserved and human specific regulators of adipocyte thermogenesis. iScience. 2025 Jun 21;28(7):112969. doi: 10.1016/j.isci.2025.112969. PMID: 40687843; PMCID: PMC12272785.
- Tóth LI, Harsányi A, Csiha S, Molnár Á, Lőrincz H, Nagy AC, Paragh G, Harangi M, Sztanek F. Semaglutide Improves Lipid Subfraction Profiles in Type 2 Diabetes: Insights from a One-Year Follow-Up Study. Int J Mol Sci. 2025 Jun 20;26(13):5951. doi: 10.3390/ijms26135951. PMID: 40649729; PMCID: PMC12250273.
- Tusnády GE, Gerdán C. TmDet 4.0: determining membrane orientation of transmembrane proteins from 3D structure. Nucleic Acids Res. 2025 Apr 25:gkaf338. doi: 10.1093/nar/gkaf338. Epub ahead of print. PMID: 40276976. 7;53(W1):W542-W546. doi: 10.1093/nar/gkaf338. PMID: 40276976; PMCID: PMC12230667.
- Ulambayar B, Ghanem AS, Nagy AC. Overnutrition in the Elderly Population: Socio-Demographic and Behavioral Risk Factors in Hungary. Nutrients. 2025 Jun 8;17(12):1954. doi: 10.3390/nu17121954. PMID: 40573065; PMCID: PMC12196326.
- Ulambayar B, Ghanem AS, Tóth Á, Nagy AC. Impact of Physical Activity and Dietary Habits on Mental Well-Being in Patients with Diabetes Mellitus. Nutrients. 2025 Mar 16;17(6):1042. doi: 10.3390/nu17061042. PMID: 40292462; PMCID: PMC11944386.
- Ulambayar B, Nagy AC. Artificial Sweeteners and Cardiovascular Risk in Hungary: Beyond Traditional Risk Factors. J Clin Med. 2025 Jun 30;14(13):4641. doi: 10.3390/jcm14134641. PMID: 40649013; PMCID: PMC12251530.
- Ungvari Z, Bartha Á, Ungvari A, Fekete M, Bianchini G, Győrffy B. Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types. Geroscience. 2025 Jan 8. doi: 10.1007/s11357-024-01494-5. Epub ahead of print. PMID: 39777709.
- Ungvari Z, Fekete M, ... Fekete JT, Varga P, Ungvari A, Győrffy B. Depression increases cancer mortality by 23-83%: a meta-analysis of 65 studies across five major cancer types. Geroscience. 2025 May 2. doi: 10.1007/s11357-025-01676-9. Epub ahead of print. PMID: 40314846.
- Ungvari Z, Fekete M, ... Munkácsy Gy, Fekete JT, ... Győrffy B. Association between red and processed meat consumption and colorectal cancer risk: a comprehensive meta-analysis of prospective studies. Geroscience. 2025 Apr 10. doi: 10.1007/s11357-025-01646-1. Epub ahead of print. PMID: 40210826.
- Ungvari Z, Fekete M, Buda A, Lehoczki A, Fekete JT, Munkácsy Gy, Varga P, Ungvari A, Győrffy B. No detectable impact of short-term treatment delays on lung cancer survival. Geroscience. 2025 May 7. doi: 10.1007/s11357-025-01684-9. Epub ahead of print. PMID: 40332453.
- Ungvari Z, Fekete M, Buda A, Lehoczki A, Munkácsy Gy, Scaffidi P, Bonaldi T, Fekete JT, Bianchini G, Varga P, Ungvari A, Győrffy B. Quantifying the impact of treatment delays on breast cancer survival outcomes: a comprehensive meta-analysis. Geroscience. 2025 Jun 10. doi: 10.1007/s11357-025-01719-1. Epub ahead of print. PMID: 40490647.
- Ungvari Z, Fekete M, Fekete JT, ... Munkácsy Gy, Varga P, Ungvari A, Győrffy B. Treatment delay significantly increases mortality in colorectal cancer: a meta-analysis. Geroscience. 2025 Apr 8. doi: 10.1007/s11357-025-01648-z. Epub ahead of print. PMID: 40198462.
- Ungvari Z, Fekete M, Fekete JT, Grosso G, Ungvari A, Győrffy B. Adherence to the Mediterranean diet and its protective effects against colorectal cancer: a meta-analysis of 26 studies with 2,217,404 participants. Geroscience. 2025 Feb;47(1):1105-1121. doi: 10.1007/s11357-024-01296-9. Epub 2024 Aug 1. PMID: 39090501; PMCID: PMC11872821.
- Ungvari Z, Fekete M, Lehoczki A, Munkácsy Gy, Fekete JT, ... Győrffy B. Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality. Geroscience. 2025 Mar 12. doi: 10.1007/s11357-025-01593-x. Epub ahead of print. PMID: 40072786.
- Ungvari Z, Fekete M, Lehoczki A, Munkácsy Gy, Fekete JT, ... Győrffy B. Sleep disorders increase the risk of dementia, Alzheimer's disease, and cognitive decline: a meta-analysis. Geroscience. 2025 Apr 11. doi: 10.1007/s11357-025-01637-2. Epub ahead of print. PMID: 40214959.
- Ungvari Z, Fekete M, Varga P, Fekete JT, ... Győrffy B. Imbalanced sleep increases mortality risk by 14-34%: a meta-analysis. Geroscience. 2025 Mar 12. doi: 10.1007/s11357-025-01592-y. Epub ahead of print. PMID: 40072785.
- Ungvari Z, Fekete M, Varga P, Fekete JT, ... Menyhart O, Munkácsy Gy, ... Győrffy B. Impact of adherence to the Mediterranean diet on stroke risk. Geroscience. 2025 Jan 7. doi: 10.1007/s11357-024-01491-8. Epub ahead of print. PMID: 39777701.
- Ungvari Z, Fekete M, Varga P, Munkácsy Gy, Fekete JT, ... Győrffy B. Exercise and survival benefit in cancer patients: evidence from a comprehensive meta-analysis. Geroscience. 2025 Apr 12. doi: 10.1007/s11357-025-01647-0. Epub ahead of print. PMID: 40220151.
- Ungvari Z, Menyhart O, Lehoczki A, Fekete M, Bianchini G, Győrffy B. PCSK9 expression and cancer survival: a prognostic biomarker at the intersection of oncology and geroscience. Geroscience. 2025 Jun 27. doi: 10.1007/s11357-025-01733-3. Epub ahead of print. PMID: 40576911.
- Ungvari Z, Menyhart O, Lehoczki A, Fekete M, Fazekas-Pongor V, Ocana A, Varga P, Győrffy B. NRF2 pathway activation predicts poor prognosis in lung cancer: a cautionary note on antioxidant interventions. Geroscience. 2025 Jun 19. doi: 10.1007/s11357-025-01736-0. Epub ahead of print. PMID: 40537696.
- Varga S, Kaasen JM, Gáspári Z, Péterfia BF, Mulder FAA. Resonance assignment of the intrinsically disordered actin-binding region of Drebrin. Biomol NMR Assign. 2025 Jun 14. doi: 10.1007/s12104-025-10239-0. Epub ahead of print. PMID: 40515930.
- Varga S, Péterfia BF, Dudola D, Farkas V, Jeffries CM, Permi P, Gáspári Z. Dynamic Interchange of Local Residue-Residue Interactions in the Largely Extended Single Alpha-Helix in Drebrin. Biochem J. 2025 Apr 1:BCJ20253036. doi: 10.1042/BCJ20253036. Epub ahead of print. PMID: 40192062.
- Vidovszky MZ, Kaján GL, Böszörményi KP, ... Harrach B. Comprehensive phylogenetic analysis of newly detected rodent adenoviruses sheds light on ancient host-switches. Mol Phylogenet Evol. 2025 Jan 16;204:108287. doi: 10.1016/j.ympev.2025.108287. Epub ahead of print. PMID: 39826590.
- Virág E, Hegedűs G, Nagy Á, Pallos JP, Kutasy B. Temporal Shifts in HormoneSignaling Networks Orchestrate Soybean Floral Development Under Field Conditions: An RNA-Seq Study. Int J Mol Sci. 2025 Jul 4;26(13):6455. doi: 10.3390/ijms26136455. PMID: 40650230; PMCID: PMC12250341.
- Wéber A, Vokó Z, Kiss Z, Szatmári I, ... Kenessey I. The impact of life tables on age standardized net survival of real-life example databases. BMC Med Res Methodol. 2025 May 26;25(1):145. doi: 10.1186/s12874-025-02600-7. PMID: 40419979.
- Wolf H, Vierø AR, Széll M. CoolWalks for active mobility in urban street networks. Sci Rep. 2025 Apr 28;15(1):14911. doi: 10.1038/s41598-025-97200-2. PMID: 40295591; PMCID: PMC12038045.
- Yamazaki H, Csire G, ... Győrffy B, Takagi H, Újfalussy B. Quantum Size Effects on Andreev Transport in Nb/Au/Nb Josephson Junctions: A Combined Ab Initio and Experimental Study. Phys Rev Lett. 2025 May 16;134(19):196002. doi: 10.1103/PhysRevLett.134.196002. PMID: 40446256.
Utolsó frissítés: 2025. 07. 27.