1. Acs-Szabo, L., Papp, L.A., Sipiczki, M., Miklos, I., 2021. Genome Comparisons of the Fission Yeasts Reveal Ancient Collinear Loci Maintained by Natural Selection. J Fungi (Basel) 7, 864. https://doi.org/10.3390/jof7100864
2. Aczél, T., Körtési, T., Kun, J., Urbán, P., Bauer, W., Herczeg, R., Farkas, R., Kovács, K., Vásárhelyi, B., Karvaly, G.B., Gyenesei, A., Tuka, B., Tajti, J., Vécsei, L., Bölcskei, K., Helyes, Z., 2021. Identification of disease- and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis. J Headache Pain 22, 117. https://doi.org/10.1186/s10194-021-01285-9
3. Alcaraz-Sanabria, A., Cabañas Morafraile, E., Fernández-Hinojal, G., Velasco, G., Pérez-Segura, P., Pandiella, A., Győrffy, B., Ocaña, A., 2021. Transcriptomic Mapping of Non-Small Cell Lung Cancer K-RAS p.G12C Mutated Tumors: Identification of Surfaceome Targets and Immunologic Correlates. Front Immunol 12, 786069. https://doi.org/10.3389/fimmu.2021.786069
4. Alpár, D., Egyed, B., Bödör, C., Kovács, G.T., 2021. Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia. Cancers (Basel) 13, 5658. https://doi.org/10.3390/cancers13225658
5. Andermann, T.M., Fouladi, F., Tamburini, F.B., Sahaf, B., Tkachenko, E., Greene, C., Buckley, M.T., Brooks, E.F., Hedlin, H., Arai, S., Mackall, C.L., Miklos, D., Negrin, R.S., Fodor, A.A., Rezvani, A.R., Bhatt, A.S., 2021. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 27, 932.e1-932.e11. https://doi.org/10.1016/j.jtct.2021.07.009
6. Andrijes, R., Hejmadi, R.K., Pugh, M., Rajesh, S., Novitskaya, V., Ibrahim, M., Overduin, M., Tselepis, C., Middleton, G.W., Győrffy, B., Beggs, A.D., Berditchevski, F., 2021. Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer. Proc Natl Acad Sci U S A 118, e2011411118. https://doi.org/10.1073/pnas.2011411118
7. Anker, P., Kiss, N., Kocsis, I., Czemmel, É., Becker, K., Zakariás, S., Plázár, D., Farkas, K., Mayer, B., Nagy, N., Széll, M., Ács, N., Szalai, Z., Medvecz, M., 2021. Report of a Novel ALOX12B Mutation in Self-Improving Collodion Ichthyosis with an Overview of the Genetic Background of the Collodion Baby Phenotype. Life (Basel) 11, 624. https://doi.org/10.3390/life11070624
8. Aslan, M., Hsu, E.-C., Garcia-Marques, F.J., Bermudez, A., Liu, S., Shen, M., West, M., Zhang, C.A., Rice, M.A., Brooks, J.D., West, R., Pitteri, S.J., Győrffy, B., Stoyanova, T., 2021. Oncogene-mediated metabolic gene signature predicts breast cancer outcome. NPJ Breast Cancer 7, 141. https://doi.org/10.1038/s41523-021-00341-6
9. Babszky, G., Torma, F., Aczel, D., Bakonyi, P., Gombos, Z., Feher, J., Szabó, D., Ligeti, B., Pongor, S., Balogh, L., Pósa, A., Radak, Z., 2021. COVID-19 Infection Alters the Microbiome: Elite Athletes and Sedentary Patients Have Similar Bacterial Flora. Genes (Basel) 12, 1577. https://doi.org/10.3390/genes12101577
10. Baksa, D., Szabo, E., Kocsel, N., Galambos, A., Edes, A.E., Pap, D., Zsombok, T., Magyar, M., Gecse, K., Dobos, D., Kozak, L.R., Bagdy, G., Kokonyei, G., Juhasz, G., 2022. Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces. Front Hum Neurosci 16, 842426. https://doi.org/10.3389/fnhum.2022.842426
11. Bartha, Á., Darula, Z., Munkácsy, G., Klement, É., Nyirády, P., Győrffy, B., 2023. Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma. Int J Mol Sci 24, 4488. https://doi.org/10.3390/ijms24054488
12. Bartha, Á., Győrffy, B., 2021. TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues. Int J Mol Sci 22, 2622. https://doi.org/10.3390/ijms22052622
13. Bauer, W., Gyenesei, A., Krętowski, A., 2021. The Multifactorial Progression from the Islet Autoimmunity to Type 1 Diabetes in Children. Int J Mol Sci 22, 7493. https://doi.org/10.3390/ijms22147493
14. Beatson, R.E., Parente-Pereira, A.C., Halim, L., Cozzetto, D., Hull, C., Whilding, L.M., Martinez, O., Taylor, C.A., Obajdin, J., Luu Hoang, K.N., Draper, B., Iqbal, A., Hardiman, T., Zabinski, T., Man, F., de Rosales, R.T.M., Xie, J., Aswad, F., Achkova, D., Joseph, C.-Y.R., Ciprut, S., Adami, A., Roider, H.G., Hess-Stumpp, H., Győrffy, B., Quist, J., Grigoriadis, A., Sommer, A., Tutt, A.N.J., Davies, D.M., Maher, J., 2021. TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. Cell Rep Med 2, 100473. https://doi.org/10.1016/j.xcrm.2021.100473
15. Becsei, Á., Solymosi, N., Csabai, I., Magyar, D., 2021. Detection of antimicrobial resistance genes in urban air. Microbiologyopen 10, e1248. https://doi.org/10.1002/mbo3.1248
16. Bellanger, A., Le, D.T., Vendrell, J., Wierinckx, A., Pongor, L.S., Solassol, J., Lachuer, J., Clezardin, P., Győrffy, B., Cohen, P.A., 2021. Exploring the Significance of the Exon 4-Skipping Isoform of the ZNF217 Oncogene in Breast Cancer. Front Oncol 11, 647269. https://doi.org/10.3389/fonc.2021.647269
17. Betancourt, L.H., Gil, J., Kim, Y., Doma, V., Çakır, U., Sanchez, A., Murillo, J.R., Kuras, M., Parada, I.P., Sugihara, Y., Appelqvist, R., Wieslander, E., Welinder, C., Velasquez, E., de Almeida, N.P., Woldmar, N., Marko-Varga, M., Pawłowski, K., Eriksson, J., Szeitz, B., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Lindberg, H., Oskolas, H., Lee, B., Berge, E., Sjögren, M., Eriksson, C., Kim, D., Kwon, H.J., Knudsen, B., Rezeli, M., Hong, R., Horvatovich, P., Miliotis, T., Nishimura, T., Kato, H., Steinfelder, E., Oppermann, M., Miller, K., Florindi, F., Zhou, Q., Domont, G.B., Pizzatti, L., Nogueira, F.C.S., Horvath, P., Szadai, L., Tímár, J., Kárpáti, S., Szász, A.M., Malm, J., Fenyö, D., Ekedahl, H., Németh, I.B., Marko-Varga, G., 2021a. The human melanoma proteome atlas-Defining the molecular pathology. Clin Transl Med 11, e473. https://doi.org/10.1002/ctm2.473
18. Betancourt, L.H., Gil, J., Sanchez, A., Doma, V., Kuras, M., Murillo, J.R., Velasquez, E., Çakır, U., Kim, Y., Sugihara, Y., Parada, I.P., Szeitz, B., Appelqvist, R., Wieslander, E., Welinder, C., de Almeida, N.P., Woldmar, N., Marko-Varga, M., Eriksson, J., Pawłowski, K., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Lindberg, H., Oskolas, H., Lee, B., Berge, E., Sjögren, M., Eriksson, C., Kim, D., Kwon, H.J., Knudsen, B., Rezeli, M., Malm, J., Hong, R., Horvath, P., Szász, A.M., Tímár, J., Kárpáti, S., Horvatovich, P., Miliotis, T., Nishimura, T., Kato, H., Steinfelder, E., Oppermann, M., Miller, K., Florindi, F., Zhou, Q., Domont, G.B., Pizzatti, L., Nogueira, F.C.S., Szadai, L., Németh, I.B., Ekedahl, H., Fenyö, D., Marko-Varga, G., 2021b. The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome. Clin Transl Med 11, e451. https://doi.org/10.1002/ctm2.451
19. Bokor, J., Sutori, S., Torok, D., Gal, Z., Eszlari, N., Gyorik, D., Baksa, D., Petschner, P., Serafini, G., Pompili, M., Anderson, I.M., Deakin, B., Bagdy, G., Juhasz, G., Gonda, X., 2021. Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis. Front Psychiatry 12, 746206. https://doi.org/10.3389/fpsyt.2021.746206
20. Borbély, A., Pethő, L., Szabó, I., Al-Majidi, M., Steckel, A., Nagy, T., Kéki, S., Kalló, G., Csősz, É., Mező, G., Schlosser, G., 2021. Structural Characterization of Daunomycin-Peptide Conjugates by Various Tandem Mass Spectrometric Techniques. Int J Mol Sci 22, 1648. https://doi.org/10.3390/ijms22041648
21. Börcsök, J., Diossy, M., Sztupinszki, Z., Prosz, A., Tisza, V., Spisak, S., Rusz, O., Stormoen, D.R., Pappot, H., Csabai, I., Brunak, S., Mouw, K.W., Szallasi, Z., 2021a. Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer. Clin Cancer Res 27, 3734–3743. https://doi.org/10.1158/1078-0432.CCR-20-5037
22. Börcsök, J., Sztupinszki, Z., Bekele, R., Gao, S.P., Diossy, M., Samant, A.S., Dillon, K.M., Tisza, V., Spisák, S., Rusz, O., Csabai, I., Pappot, H., Frazier, Z.J., Konieczkowski, D.J., Liu, D., Vasani, N., Rodrigues, J.A., Solit, D.B., Hoffman-Censits, J.H., Plimack, E.R., Rosenberg, J.E., Lazaro, J.-B., Taplin, M.-E., Iyer, G., Brunak, S., Lozsa, R., Van Allen, E.M., Szüts, D., Mouw, K.W., Szallasi, Z., 2021b. Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer. Clin Cancer Res 27, 2011–2022. https://doi.org/10.1158/1078-0432.CCR-20-3316
23. Boros, Á., Albert, M., Urbán, P., Herczeg, R., Gáspár, G., Balázs, B., Cságola, A., Pankovics, P., Gyenesei, A., Reuter, G., 2022. Unusual “Asian-origin” 2c to 2b point mutant canine parvovirus (Parvoviridae) and canine astrovirus (Astroviridae) co-infection detected in vaccinated dogs with an outbreak of severe haemorrhagic gastroenteritis with high mortality rate in Hungary. Vet Res Commun 46, 1355–1361. https://doi.org/10.1007/s11259-022-09997-2
24. Borsodi, K., Balla, H., Molnár, P.J., Lénárt, Á., Kenessey, I., Horváth, A., Keszthelyi, A., Romics, M., Majoros, A., Nyirády, P., Offermanns, S., Benyó, Z., 2021. Signaling Pathways Mediating Bradykinin-Induced Contraction in Murine and Human Detrusor Muscle. Front Med (Lausanne) 8, 745638. https://doi.org/10.3389/fmed.2021.745638
25. Breitenecker, K., Homolya, M., Luca, A.C., Lang, V., Trenk, C., Petroczi, G., Mohrherr, J., Horvath, J., Moritsch, S., Haas, L., Kurnaeva, M., Eferl, R., Stoiber, D., Moriggl, R., Bilban, M., Obenauf, A.C., Ferran, C., Dome, B., Laszlo, V., Győrffy, B., Dezso, K., Moldvay, J., Casanova, E., Moll, H.P., 2021. Down-regulation of A20 promotes immune escape of lung adenocarcinomas. Sci Transl Med 13, eabc3911. https://doi.org/10.1126/scitranslmed.abc3911
26. Büki, G., Zsigmond, A., Czakó, M., Szalai, R., Antal, G., Farkas, V., Fekete, G., Nagy, D., Széll, M., Tihanyi, M., Melegh, B., Hadzsiev, K., Bene, J., 2021. Genotype-Phenotype Associations in Patients With Type-1, Type-2, and Atypical NF1 Microdeletions. Front Genet 12, 673025. https://doi.org/10.3389/fgene.2021.673025
27. Bykowska-Derda, A., Darr, R., Czlapka-Matyasik, M., Horvath, P., 2021. Short fat-adaptation diet impact on a consecutive day of interval exercise performance. Acta Sci Pol Technol Aliment 20, 47–54. https://doi.org/10.17306/J.AFS.0828
28. Canal, D., Garcia-Gonzalez, F., Garamszegi, L.Z., 2021. Experimentally constrained early reproduction shapes life history trajectories and behaviour. Sci Rep 11, 4442. https://doi.org/10.1038/s41598-021-83703-1
29. Chakravarty, S., Csikász-Nagy, A., 2021. Systematic analysis of noise reduction properties of coupled and isolated feed-forward loops. PLoS Comput Biol 17, e1009622. https://doi.org/10.1371/journal.pcbi.1009622
30. Csikány, N., Kiss, Á., Déri, M., Fekete, F., Minus, A., Tóth, K., Temesvári, M., Sárváry, E., Bihari, L., Gerlei, Z., Kóbori, L., Monostory, K., 2021. Clinical significance of personalized tacrolimus dosing by adjusting to donor CYP3A-status in liver transplant recipients. Br J Clin Pharmacol 87, 1790–1800. https://doi.org/10.1111/bcp.14566
31. Csikós, A., Kozma, B., Pór, Á., Kovács, I., Lampé, R., Miklós, I., Takacs, P., 2021b. Zinc Transporter 9 (SLC30A9) Expression Is Decreased in the Vaginal Tissues of Menopausal Women. Biol Trace Elem Res 199, 4011–4019. https://doi.org/10.1007/s12011-020-02525-w
32. Csizmadia, G., Erdős, G., Tordai, H., Padányi, R., Tosatto, S., Dosztányi, Z., Hegedűs, T., 2021. The MemMoRF database for recognizing disordered protein regions interacting with cellular membranes. Nucleic Acids Res 49, D355–D360. https://doi.org/10.1093/nar/gkaa954
33. Csuhai, É.A., Nagy, A.C., Szőllősi, G.J., Veres-Balajti, I., 2021. Impact Analysis of 20-Week Multimodal Progressive Functional-Proprioceptive Training among Sedentary Workers Affected by Non-Specific Low-Back Pain: An Interventional Cohort Study. Int J Environ Res Public Health 18, 10592. https://doi.org/10.3390/ijerph182010592
34. Czimer, D., Porok, K., Csete, D., Gyüre, Z., Lavró, V., Fülöp, K., Chen, Z., Gyergyák, H., Tusnády, G.E., Burgess, S.M., Mócsai, A., Váradi, A., Varga, M., 2021. A New Zebrafish Model for Pseudoxanthoma Elasticum. Front Cell Dev Biol 9, 628699. https://doi.org/10.3389/fcell.2021.628699
35. Danis, J., Kelemen, E., Rajan, N., Nagy, N., Széll, M., Ádám, É., 2021. TRAF3 and NBR1 both influence the effect of the disease-causing CYLD(Arg936X) mutation on NF-κB activity. Exp Dermatol 30, 1705–1710. https://doi.org/10.1111/exd.14365
36. Daragó, A., Szabó, E., Barkó, D., Schwegler, G., Szabó, R.P., Nagy, A.C., Nemes, B., 2021. Effects of Kidney Transplantation on Valvular Heart Diseases. Transplant Proc 53, 1433–1438. https://doi.org/10.1016/j.transproceed.2021.01.043
37. Dastjerdi, A., Jeckel, S., Davies, H., Irving, J., Longue, C., Plummer, C., Vidovszky, M.Z., Harrach, B., Chantrey, J., Martineau, H., Williams, J., 2022. Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus). Transbound Emerg Dis 69, 3097–3102. https://doi.org/10.1111/tbed.14374
38. Déri, M., Szakál-Tóth, Z., Fekete, F., Mangó, K., Incze, E., Minus, A., Merkely, B., Sax, B., Monostory, K., 2021. CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients. Sci Rep 11, 21389. https://doi.org/10.1038/s41598-021-00942-y
39. Díaz-Gil, L., Brasó-Maristany, F., Locatelli, C., Centa, A., Győrffy, B., Ocaña, A., Prat, A., Pandiella, A., 2021. Modelling hypersensitivity to trastuzumab defines biomarkers of response in HER2 positive breast cancer. J Exp Clin Cancer Res 40, 313. https://doi.org/10.1186/s13046-021-02098-z
40. Diosdi, A., Hirling, D., Kovacs, M., Toth, T., Harmati, M., Koos, K., Buzas, K., Piccinini, F., Horvath, P., 2021a. A quantitative metric for the comparative evaluation of optical clearing protocols for 3D multicellular spheroids. Comput Struct Biotechnol J 19, 1233–1243. https://doi.org/10.1016/j.csbj.2021.01.040
41. Diosdi, A., Hirling, D., Kovacs, M., Toth, T., Harmati, M., Koos, K., Buzas, K., Piccinini, F., Horvath, P., 2021b. Cell lines and clearing approaches: a single-cell level 3D light-sheet fluorescence microscopy dataset of multicellular spheroids. Data Brief 36, 107090. https://doi.org/10.1016/j.dib.2021.107090
42. Dobó, M., Foroughbakhshfasaei, M., Horváth, P., Szabó, Z.-I., Tóth, G., 2022. Chiral separation of oxazolidinone analogues by liquid chromatography on polysaccharide stationary phases using polar organic mode. J Chromatogr A 1662, 462741. https://doi.org/10.1016/j.chroma.2021.462741
43. Dobson, L., Tusnády, G.E., 2021. MemDis: Predicting Disordered Regions in Transmembrane Proteins. Int J Mol Sci 22, 12270. https://doi.org/10.3390/ijms222212270
44. Erdős, G., Pajkos, M., Dosztányi, Z., 2021. IUPred3: prediction of protein disorder enhanced with unambiguous experimental annotation and visualization of evolutionary conservation. Nucleic Acids Res 49, W297–W303. https://doi.org/10.1093/nar/gkab408
45. Eszlari, N., Bagyura, Z., Millinghoffer, A., Nagy, T., Juhasz, G., Antal, P., Merkely, B., Bagdy, G., 2021a. Catenin Alpha 2 May Be a Biomarker or Potential Drug Target in Psychiatric Disorders with Perseverative Negative Thinking. Pharmaceuticals (Basel) 14, 850. https://doi.org/10.3390/ph14090850
46. Eszlari, N., Bruncsics, B., Millinghoffer, A., Hullam, G., Petschner, P., Gonda, X., Breen, G., Antal, P., Bagdy, G., Deakin, J.F.W., Juhasz, G., 2021b. Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake. Nutrients 13, 4396. https://doi.org/10.3390/nu13124396
47. Far, D., Takács, N., Gyurkovszky, M., Solymosi, N., Farkas, R., 2021. Ticks and Tick-Borne Infections of Dogs in Two Jordanian Shelters. Vector Borne Zoonotic Dis 21, 573–578. https://doi.org/10.1089/vbz.2021.0026
48. Faragó, Z., Mirzahosseini, A., Horváth, D., Pálla, T., Horváth, P., Perczel, A., Noszál, B., 2021. Solution Structure and Acid-Base Properties of Reduced α-Conotoxin MI. Chem Biodivers 18, e2100464. https://doi.org/10.1002/cbdv.202100464
49. Farkas, G., Kocsis, Z.S., Székely, G., Dobozi, M., Kenessey, I., Polgár, C., Jurányi, Z., 2021. Smoking, chromosomal aberrations, and cancer incidence in healthy subjects. Mutat Res Genet Toxicol Environ Mutagen 867, 503373. https://doi.org/10.1016/j.mrgentox.2021.503373
50. Fekete, F., Mangó, K., Déri, M., Incze, E., Minus, A., Monostory, K., 2021. Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects. Sci Rep 11, 17081. https://doi.org/10.1038/s41598-021-96590-3
51. Fekete, J.T., Győrffy, B., 2023. New Transcriptomic Biomarkers of 5-Fluorouracil Resistance. Int J Mol Sci 24, 1508. https://doi.org/10.3390/ijms24021508
52. Fekete, Z., Vass, E., Balajth, R., Tana, Ü., Nagy, A.C., Domján, N., Égerházi, A., Kuritárné, I.S., 2022. Regrouping scalets: Psychometric properties of the theory of mind picture stories task in a schizophrenic sample. Neuropsychol Rehabil 32, 2227–2247. https://doi.org/10.1080/09602011.2021.1930559
53. Ferenczi, S., Solymosi, N., Horváth, I., Szeőcs, N., Grózer, Z., Kuti, D., Juhász, B., Winkler, Z., Pankotai, T., Sükösd, F., Stágel, A., Paholcsek, M., Dóra, D., Nagy, N., Kovács, K.J., Zanoni, I., Szallasi, Z., 2021. Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria. Mol Ther Methods Clin Dev 20, 218–226. https://doi.org/10.1016/j.omtm.2020.11.010
54. Fesu, D., Bohacs, A., Hidvegi, E., Matics, Z., Polivka, L., Horvath, P., Czaller, I., Sutto, Z., Eszes, N., Vincze, K., Muller, V., 2022. Remdesivir in Solid Organ Recipients for COVID-19 Pneumonia. Transplant Proc 54, 2567–2569. https://doi.org/10.1016/j.transproceed.2022.10.043
55. Fogarassy, G., Vathy-Fogarassy, Á., Kenessey, I., Veress, G., Polgár, C., Forster, T., 2021. Preventing cancer therapy-related heart failure: the need for novel studies. J Cardiovasc Med (Hagerstown) 22, 459–468. https://doi.org/10.2459/JCM.0000000000001115
56. Fuentes-Antrás, J., Alcaraz-Sanabria, A.L., Morafraile, E.C., Noblejas-López, M.D.M., Galán-Moya, E.M., Baliu-Pique, M., López-Cade, I., García-Barberán, V., Pérez-Segura, P., Manzano, A., Pandiella, A., Győrffy, B., Ocaña, A., 2021. Mapping of Genomic Vulnerabilities in the Post-Translational Ubiquitination, SUMOylation and Neddylation Machinery in Breast Cancer. Cancers (Basel) 13, 833. https://doi.org/10.3390/cancers13040833
57. Gángó, A., Kiss, R., Farkas, P., Hanna, E., Demeter, J., Deák, B., Lévai, D., Kotmayer, L., Alpár, D., Matolcsy, A., Bödör, C., Mátrai, Z., Timár, B., 2022. Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax. Pathology 54, 95–103. https://doi.org/10.1016/j.pathol.2021.04.008
58. Garcia-Garcia, S., Rodrigo-Faus, M., Fonseca, N., Manzano, S., Győrffy, B., Ocaña, A., Bragado, P., Porras, A., Gutierrez-Uzquiza, A., 2021. HGK promotes metastatic dissemination in prostate cancer. Sci Rep 11, 12287. https://doi.org/10.1038/s41598-021-91292-2
59. Gargya, P., Bálint, B.L., 2021. Histological Grade of Endometrioid Endometrial Cancer and Relapse Risk Can Be Predicted with Machine Learning from Gene Expression Data. Cancers (Basel) 13, 4348. https://doi.org/10.3390/cancers13174348
60. Gecse, K., Baksa, D., Dobos, D., Aranyi, C.S., Galambos, A., Kocsel, N., Szabó, E., Kökönyei, G., Emri, M., Bagdy, G., Juhasz, G., 2021. Sex Differences of Periaqueductal Grey Matter Functional Connectivity in Migraine. Front Pain Res (Lausanne) 2, 767162. https://doi.org/10.3389/fpain.2021.767162
61. Gieszer, B., Megyesfalvi, Z., Dulai, V., Papay, J., Kovalszky, I., Timar, J., Fillinger, J., Harko, T., Pipek, O., Teglasi, V., Regos, E., Papp, G., Szallasi, Z., Laszlo, V., Renyi-Vamos, F., Galffy, G., Bodor, C., Dome, B., Moldvay, J., 2021. EGFR variant allele frequency predicts EGFR-TKI efficacy in lung adenocarcinoma: a multicenter study. Transl Lung Cancer Res 10, 662–674. https://doi.org/10.21037/tlcr-20-814
62. Gleizes, A., Triki, M., Bonnet, S., Baccari, N., Jimenez-Dominguez, G., Covinhes, A., Pirot, N., Blache, P., Yuan, R., Győrffy, B., Cavaillès, V., Lapierre, M., 2021. RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer. Cancers (Basel) 13, 3192. https://doi.org/10.3390/cancers13133192
63. Gokuldass, A., Schina, A., Lauss, M., Harbst, K., Chamberlain, C.A., Draghi, A., Westergaard, M.C.W., Nielsen, M., Papp, K., Sztupinszki, Z., Csabai, I., Svane, I.M., Szallasi, Z., Jönsson, G., Donia, M., 2022. Transcriptomic signatures of tumors undergoing T cell attack. Cancer Immunol Immunother 71, 553–563. https://doi.org/10.1007/s00262-021-03015-1
64. Gombos, K., Földi, M., Kiss, S., Herczeg, R., Gyenesei, A., Geiger, L., Csabai, D., Futács, K., Nagy, T., Miseta, A., Somogyi, B.A., Hegyi, P., Szentesi, A., 2020. Analysis of COVID-19-Related RT-qPCR Test Results in Hungary: Epidemiology, Diagnostics, and Clinical Outcome. Front Med (Lausanne) 7, 625673. https://doi.org/10.3389/fmed.2020.625673
65. Gombos, K., Gálik, B., Kalács, K.I., Gödöny, K., Várnagy, Á., Alpár, D., Bódis, J., Gyenesei, A., Kovács, G.L., 2021a. NGS-Based Application for Routine Non-Invasive Pre-Implantation Genetic Assessment in IVF. Int J Mol Sci 22, 2443. https://doi.org/10.3390/ijms22052443
66. Gombos, K., Herczeg, R., Erőss, B., Kovács, S.Z., Uzzoli, A., Nagy, T., Kiss, S., Szakács, Z., Imrei, M., Szentesi, A., Nagy, A., Fábián, A., Hegyi, P., Gyenesei, A., 2021b. Translating Scientific Knowledge to Government Decision Makers Has Crucial Importance in the Management of the COVID-19 Pandemic. Popul Health Manag 24, 35–45. https://doi.org/10.1089/pop.2020.0159
67. Gonda, X., Eszlari, N., Torok, D., Gal, Z., Bokor, J., Millinghoffer, A., Baksa, D., Petschner, P., Antal, P., Breen, G., Juhasz, G., Bagdy, G., 2021. Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Transl Psychiatry 11, 337. https://doi.org/10.1038/s41398-021-01436-1
68. Grexa, I., Diosdi, A., Harmati, M., Kriston, A., Moshkov, N., Buzas, K., Pietiäinen, V., Koos, K., Horvath, P., 2021. SpheroidPicker for automated 3D cell culture manipulation using deep learning. Sci Rep 11, 14813. https://doi.org/10.1038/s41598-021-94217-1
69. Gyimesi, M., Rauscher, A.Á., Suthar, S.K., Hamow, K.Á., Oravecz, K., Lőrincz, I., Borhegyi, Z., Déri, M.T., Kiss, Á.F., Monostory, K., Szabó, P.T., Nag, S., Tomasic, I., Krans, J., Tierney, P.J., Kovács, M., Kornya, L., Málnási-Csizmadia, A., 2021. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2. J Pharmacol Exp Ther 376, 358–373. https://doi.org/10.1124/jpet.120.000167
70. Győrffy, B., 2023. Discovery and ranking of the most robust prognostic biomarkers in serous ovarian cancer. Geroscience. https://doi.org/10.1007/s11357-023-00742-4
71. Győrffy, B., 2021. Survival analysis across the entire transcriptome identifies biomarkers with the highest prognostic power in breast cancer. Comput Struct Biotechnol J 19, 4101–4109. https://doi.org/10.1016/j.csbj.2021.07.014
72. Gyorik, D., Eszlari, N., Gal, Z., Torok, D., Baksa, D., Kristof, Z., Sutori, S., Petschner, P., Juhasz, G., Bagdy, G., Gonda, X., 2021. Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress. Front Psychiatry 12, 687487. https://doi.org/10.3389/fpsyt.2021.687487
73. Harmat, Z., Dudola, D., Gáspári, Z., 2021. DIPEND: An Open-Source Pipeline to Generate Ensembles of Disordered Segments Using Neighbor-Dependent Backbone Preferences. Biomolecules 11, 1505. https://doi.org/10.3390/biom11101505
74. Heinen, A., Gödecke, S., Flögel, U., Miklos, D., Bottermann, K., Spychala, A., Gödecke, A., 2021. 4-hydroxytamoxifen does not deteriorate cardiac function in cardiomyocyte-specific MerCreMer transgenic mice. Basic Res Cardiol 116, 8. https://doi.org/10.1007/s00395-020-00841-9
75. Hernansaiz-Ballesteros, R.D., Földi, C., Cardelli, L., Nagy, L.G., Csikász-Nagy, A., 2021. Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints. Sci Rep 11, 11122. https://doi.org/10.1038/s41598-021-90384-3
76. Herold, Z., Herold, M., Herczeg, G., Fodor, A., Szasz, A.M., Dank, M., Somogyi, A., 2022. High plasma CD40 ligand level is associated with more advanced stages and worse prognosis in colorectal cancer. World J Clin Cases 10, 4084–4096. https://doi.org/10.12998/wjcc.v10.i13.4084
77. Herold, Z., Szasz, A.M., Dank, M., 2021. Evidence based tools to improve efficiency of currently administered oncotherapies for tumors of the hepatopancreatobiliary system. World J Gastrointest Oncol 13, 1109–1120. https://doi.org/10.4251/wjgo.v13.i9.1109
78. Horváth, E., Dályai, L., Szabó, E., Barna, T., Kalmár, L., Posta, J., Sipiczki, M., Csoma, H., Miklós, I., 2021. The antagonistic Metschnikowia andauensis produces extracellular enzymes and pulcherrimin, whose production can be promoted by the culture factors. Sci Rep 11, 10593. https://doi.org/10.1038/s41598-021-89982-y
79. Horváth, M., Nagy, G., Zsindely, N., Bodai, L., Horváth, P., Vágvölgyi, C., Nosanchuk, J.D., Tóth, R., Gácser, A., 2021. Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation. mSystems 6, e00163-21. https://doi.org/10.1128/mSystems.00163-21
80. Horvath, P., Yurttas, C., Baur, I., Steidle, C., Reymond, M.A., Girotti, P.N.C., Königsrainer, A., Königsrainer, I., 2022. Current Medical Care Situation of Patients in Germany Undergoing Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC). Cancers (Basel) 14, 1443. https://doi.org/10.3390/cancers14061443
81. Horvath, P., Yurttas, C., Beckert, S., Königsrainer, A., Königsrainer, I., 2021. Twelve-Year Single Center Experience Shows Safe Implementation of Developed Peritoneal Surface Malignancy Treatment Protocols for Gastrointestinal and Gynecological Primary Tumors. Cancers (Basel) 13, 2471. https://doi.org/10.3390/cancers13102471
82. Horvath, P.M., Chanaday, N.L., Alten, B., Kavalali, E.T., Monteggia, L.M., 2021. A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength. Cell Rep 36, 109467. https://doi.org/10.1016/j.celrep.2021.109467
83. Jablonszky, M., Zsebők, S., Laczi, M., Nagy, G., Vaskuti, É., Garamszegi, L.Z., 2021. The effect of social environment on bird song: listener-specific expression of a sexual signal. Behav Ecol 32, 395–406. https://doi.org/10.1093/beheco/araa132
84. Jankó, L., Kovács, T., Laczik, M., Sári, Z., Ujlaki, G., Kis, G., Horváth, I., Antal, M., Vígh, L., Bálint, B.L., Uray, K., Bai, P., 2021. Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation. Cells 10, 1387. https://doi.org/10.3390/cells10061387
85. Javanbakht, M., Mashayekhi, A., Branagan-Harris, M., Horvath, P., Königsrainer, A., Reymond, M.A., Yaghoubi, M., 2022. Cost-effectiveness analysis of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in patients with gastric cancer and peritoneal metastasis. Eur J Surg Oncol 48, 188–196. https://doi.org/10.1016/j.ejso.2021.08.024
86. Jenei, A., Kalló, G., Dajnoki, Z., Gáspár, K., Szegedi, A., Kapitány, A., Csősz, É., 2021. Detection of Antimicrobial Peptides in Stratum Corneum by Mass Spectrometry. Int J Mol Sci 22, 4233. https://doi.org/10.3390/ijms22084233
87. Johnsrud, A., Craig, J., Baird, J., Spiegel, J., Muffly, L., Zehnder, J., Tamaresis, J., Negrin, R., Johnston, L., Arai, S., Shizuru, J., Lowsky, R., Meyer, E., Weng, W.-K., Shiraz, P., Rezvani, A., Latchford, T., Mackall, C., Miklos, D., Frank, M., Sidana, S., 2021. Incidence and risk factors associated with bleeding and thrombosis following chimeric antigen receptor T-cell therapy. Blood Adv 5, 4465–4475. https://doi.org/10.1182/bloodadvances.2021004716
88. Kadenczki, O., Nagy, A.C., Kiss, C., 2021. Prevalence of Undernutrition and Effect of Body Weight Loss on Survival among Pediatric Cancer Patients in Northeastern Hungary. Int J Environ Res Public Health 18, 1478. https://doi.org/10.3390/ijerph18041478
89. Kalló, G., Varga, A.K., Szabó, J., Emri, M., Tőzsér, J., Csutak, A., Csősz, É., 2021. Reduced Level of Tear Antimicrobial and Immunomodulatory Proteins as a Possible Reason for Higher Ocular Infections in Diabetic Patients. Pathogens 10, 883. https://doi.org/10.3390/pathogens10070883
90. Kárai, B., Tisza, K., Eperjesi, O., Nagy, A.C., Ujfalusi, A., Kelemen, Á., Szegedi, I., Kiss, C., Kappelmayer, J., Hevessy, Z., 2021. A Novel Method for the Evaluation of Bone Marrow Samples from Patients with Pediatric B-Cell Acute Lymphoblastic Leukemia-Multidimensional Flow Cytometry. Cancers (Basel) 13, 5044. https://doi.org/10.3390/cancers13205044
91. Kassay, N., Mótyán, J.A., Matúz, K., Golda, M., Tőzsér, J., 2021. Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases. Life (Basel) 11, 127. https://doi.org/10.3390/life11020127
92. Kelemen, E., Bozó, R., Groma, G., Bata-Csörgő, Z., Kemény, L., Danis, J., Széll, M., 2021. The Psoriatic Nonlesional Skin: A Battlefield between Susceptibility and Protective Factors. J Invest Dermatol 141, 2785–2790. https://doi.org/10.1016/j.jid.2021.05.020
93. Képíró, L., Széll, M., Kovács, L., Keszthelyi, P., Kemény, L., Gyulai, R., 2021. The association of HLA-C and ERAP1 polymorphisms in early and late onset psoriasis and psoriatic arthritis patients of Hungary. Postepy Dermatol Alergol 38, 43–51. https://doi.org/10.5114/ada.2021.104277
94. Kerekes, K., Trexler, M., Bányai, L., Patthy, L., 2021. Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog. Cells 10, 3496. https://doi.org/10.3390/cells10123496
95. Király, M., Kiss, B.D., Horváth, P., Drahos, L., Mirzahosseini, A., Pálfy, G., Antal, I., Ludányi, K., 2021. Investigating thermal stability based on the structural changes of lactase enzyme by several orthogonal methods. Biotechnol Rep (Amst) 30, e00637. https://doi.org/10.1016/j.btre.2021.e00637
96. Kiss, Z., Wittmann, I., Polivka, L., Surján, G., Surján, O., Barcza, Z., Molnár, G.A., Nagy, D., Müller, V., Bogos, K., Nagy, P., Kenessey, I., Wéber, A., Pálosi, M., Szlávik, J., Schaff, Z., Szekanecz, Z., Müller, C., Kásler, M., Vokó, Z., 2022. Nationwide Effectiveness of First and Second SARS-CoV2 Booster Vaccines During the Delta and Omicron Pandemic Waves in Hungary (HUN-VE 2 Study). Front Immunol 13, 905585. https://doi.org/10.3389/fimmu.2022.905585
97. Kökönyei, G., Galambos, A., Kocsel, N., Szabó, E., Édes, A.E., Gecse, K., Baksa, D., Pap, D., Kozák, L.R., Bagdy, G., Juhász, G., 2021. Inter-individual differences in pain anticipation and pain perception in migraine: Neural correlates of migraine frequency and cortisol-to-dehydroepiandrosterone sulfate (DHEA-S) ratio. PLoS One 16, e0261570. https://doi.org/10.1371/journal.pone.0261570
98. Koncz, S., Papp, N., Menczelesz, N., Pothorszki, D., Bagdy, G., 2021. EEG and Sleep Effects of Tramadol Suggest Potential Antidepressant Effects with Different Mechanisms of Action. Pharmaceuticals (Basel) 14, 431. https://doi.org/10.3390/ph14050431
99. Koos, K., Oláh, G., Balassa, T., Mihut, N., Rózsa, M., Ozsvár, A., Tasnadi, E., Barzó, P., Faragó, N., Puskás, L., Molnár, G., Molnár, J., Tamás, G., Horvath, P., 2021. Automatic deep learning-driven label-free image-guided patch clamp system. Nat Commun 12, 936. https://doi.org/10.1038/s41467-021-21291-4
100. Köteles, I., Mazák, K., Tóth, G., Horváth, P., Kiss, E., Tűz, B., Hosztafi, S., 2021. Synthesis of 3-O-Carboxyalkyl Morphine Derivatives and Characterization of Their Acid-Base Properties. Chem Biodivers 18, e2100135. https://doi.org/10.1002/cbdv.202100135
101. Kovács, Z.Z.A., Szűcs, G., Freiwan, M., Kovács, M.G., Márványkövi, F.M., Dinh, H., Siska, A., Farkas, K., Kovács, F., Kriston, A., Horváth, P., Kővári, B., Cserni, B.G., Cserni, G., Földesi, I., Csont, T., Sárközy, M., 2021. Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy. Sci Rep 11, 17495. https://doi.org/10.1038/s41598-021-96815-5
102. Kozák, E., Szikora, B., Iliás, A., Jani, P.K., Hegyi, Z., Matula, Z., Dedinszki, D., Tőkési, N., Fülöp, K., Pomozi, V., Várady, G., Bakos, É., Tusnády, G.E., Kacskovics, I., Váradi, A., 2021. Creation of the first monoclonal antibody recognizing an extracellular epitope of hABCC6. FEBS Lett 595, 789–798. https://doi.org/10.1002/1873-3468.13991
103. Kraboth, Z., Kajtár, B., Gálik, B., Gyenesei, A., Miseta, A., Kalman, B., 2021. Involvement of the Catecholamine Pathway in Glioblastoma Development. Cells 10, 549. https://doi.org/10.3390/cells10030549
104. Krafft, U., Olah, C., Reis, H., Kesch, C., Darr, C., Grünwald, V., Tschirdewahn, S., Hadaschik, B., Horvath, O., Kenessey, I., Nyirady, P., Varadi, M., Modos, O., Csizmarik, A., Szarvas, T., 2021. High Serum PD-L1 Levels Are Associated with Poor Survival in Urothelial Cancer Patients Treated with Chemotherapy and Immune Checkpoint Inhibitor Therapy. Cancers (Basel) 13, 2548. https://doi.org/10.3390/cancers13112548
105. Krenhardt, K., Markó, G., Jablonszky, M., Török, J., Garamszegi, L.Z., 2021. Sex-dependent risk-taking behaviour towards different predatory stimuli in the collared flycatcher. Behav Processes 186, 104360. https://doi.org/10.1016/j.beproc.2021.104360
106. Kuehn, J., Espinoza-Sanchez, N.A., Teixeira, F.C.O.B., Pavão, M.S.G., Kiesel, L., Győrffy, B., Greve, B., Götte, M., 2021. Prognostic significance of hedgehog signaling network-related gene expression in breast cancer patients. J Cell Biochem 122, 577–597. https://doi.org/10.1002/jcb.29886
107. Kumar, A., Doan, V.M., Kunkli, B., Csősz, É., 2021. Construction of Unified Human Antimicrobial and Immunomodulatory Peptide Database and Examination of Antimicrobial and Immunomodulatory Peptides in Alzheimer’s Disease Using Network Analysis of Proteomics Datasets. Front Genet 12, 633050. https://doi.org/10.3389/fgene.2021.633050
108. Lánczky, A., Győrffy, B., 2021. Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation. J Med Internet Res 23, e27633. https://doi.org/10.2196/27633
109. Langó, T., Kuffa, K., Tóth, G., Turiák, L., Drahos, L., Tusnády, G.E., 2022. Comprehensive Discovery of the Accessible Primary Amino Group-Containing Segments from Cell Surface Proteins by Fine-Tuning a High-Throughput Biotinylation Method. Int J Mol Sci 24, 273. https://doi.org/10.3390/ijms24010273
110. Lazary, J., Eszlari, N., Kriko, E., Tozser, D., Dome, P., Deakin, J.F.W., Juhasz, G., Bagdy, G., 2021. Genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants. Neurosci Lett 744, 135600. https://doi.org/10.1016/j.neulet.2020.135600
111. Lehotzky, A., Oláh, J., Fekete, J.T., Szénási, T., Szabó, E., Győrffy, B., Várady, G., Ovádi, J., 2021. Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models. Front Mol Biosci 8, 666026. https://doi.org/10.3389/fmolb.2021.666026
112. Lin, W.-Y., Fordham, S.E., Hungate, E., Sunter, N.J., Elstob, C., Xu, Y., Park, C., Quante, A., Strauch, K., Gieger, C., Skol, A., Rahman, T., Sucheston-Campbell, L., Wang, J., Hahn, T., Clay-Gilmour, A.I., Jones, G.L., Marr, H.J., Jackson, G.H., Menne, T., Collin, M., Ivey, A., Hills, R.K., Burnett, A.K., Russell, N.H., Fitzgibbon, J., Larson, R.A., Le Beau, M.M., Stock, W., Heidenreich, O., Alharbi, A., Allsup, D.J., Houlston, R.S., Norden, J., Dickinson, A.M., Douglas, E., Lendrem, C., Daly, A.K., Palm, L., Piechocki, K., Jeffries, S., Bornhäuser, M., Röllig, C., Altmann, H., Ruhnke, L., Kunadt, D., Wagenführ, L., Cordell, H.J., Darlay, R., Andersen, M.K., Fontana, M.C., Martinelli, G., Marconi, G., Sanz, M.A., Cervera, J., Gómez-Seguí, I., Cluzeau, T., Moreilhon, C., Raynaud, S., Sill, H., Voso, M.T., Lo-Coco, F., Dombret, H., Cheok, M., Preudhomme, C., Gale, R.E., Linch, D., Gaal-Wesinger, J., Masszi, A., Nowak, D., Hofmann, W.-K., Gilkes, A., Porkka, K., Milosevic Feenstra, J.D., Kralovics, R., Grimwade, D., Meggendorfer, M., Haferlach, T., Krizsán, S., Bödör, C., Stölzel, F., Onel, K., Allan, J.M., 2021. Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nat Commun 12, 6233. https://doi.org/10.1038/s41467-021-26551-x
113. Linkner, T.R., Ambrus, V., Kunkli, B., Szojka, Z.I., Kalló, G., Csősz, É., Kumar, A., Emri, M., Tőzsér, J., Mahdi, M., 2021. Cellular Proteo-Transcriptomic Changes in the Immediate Early-Phase of Lentiviral Transduction. Microorganisms 9, 2207. https://doi.org/10.3390/microorganisms9112207
114. Listik, E., Horst, B., Choi, A.S., Lee, N.Y., Győrffy, B., Mythreye, K., 2021. A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors. PLoS One 16, e0249558. https://doi.org/10.1371/journal.pone.0249558
115. Liszkay, G., Kiss, Z., Gyulai, R., Oláh, J., Holló, P., Emri, G., Csejtei, A., Kenessey, I., Benedek, A., Polányi, Z., Nagy-Erdei, Z., Daniel, A., Knollmajer, K., Várnai, M., Vokó, Z., Nagy, B., Rokszin, G., Fábián, I., Barcza, Z., Polgár, C., 2020. Changing Trends in Melanoma Incidence and Decreasing Melanoma Mortality in Hungary Between 2011 and 2019: A Nationwide Epidemiological Study. Front Oncol 10, 612459. https://doi.org/10.3389/fonc.2020.612459
116. Liszkay, G., Mátrai, Z., Czirbesz, K., Jani, N., Bencze, E., Kenessey, I., 2021. Predictive and Prognostic Value of BRAF and NRAS Mutation of 159 Sentinel Lymph Node Cases in Melanoma-A Retrospective Single-Institute Study. Cancers (Basel) 13, 3302. https://doi.org/10.3390/cancers13133302
117. Lőrincz, O., Tóth, J., Molnár, L., Miklós, I., Pántya, K., Megyesi, M., Somogyi, E., Csiszovszki, Z., Tőke, E.R., 2021. In Silico Model Estimates the Clinical Trial Outcome of Cancer Vaccines. Cells 10, 3048. https://doi.org/10.3390/cells10113048
118. Majláth, I., Éva, C., Hamow, K.Á., Kun, J., Pál, M., Rahman, A., Palla, B., Nagy, Z., Gyenesei, A., Szalai, G., Janda, T., 2022. Methylglyoxal induces stress signaling and promotes the germination of maize at low temperature. Physiol Plant 174, e13609. https://doi.org/10.1111/ppl.13609
119. Menyhárt, O., Fekete, J.T., Győrffy, B., 2021. Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies. Carcinogenesis 42, 804–813. https://doi.org/10.1093/carcin/bgab024
120. Menyhárt, O., Győrffy, B., 2021. Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosis. Comput Struct Biotechnol J 19, 949–960. https://doi.org/10.1016/j.csbj.2021.01.009
121. Menyhart, O., Weltz, B., Győrffy, B., 2021. MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction. PLoS One 16, e0245824. https://doi.org/10.1371/journal.pone.0245824
122. Mészáros, B., Hajdu-Soltész, B., Zeke, A., Dosztányi, Z., 2021. Mutations of Intrinsically Disordered Protein Regions Can Drive Cancer but Lack Therapeutic Strategies. Biomolecules 11, 381. https://doi.org/10.3390/biom11030381
123. Meszaros, M., Horvath, P., Kis, A., Kunos, L., Tarnoki, A.D., Tarnoki, D.L., Lazar, Z., Bikov, A., 2021. Circulating levels of clusterin and complement factor H in patients with obstructive sleep apnea. Biomark Med 15, 323–330. https://doi.org/10.2217/bmm-2020-0533
124. Miczi, M., Diós, Á., Bozóki, B., Tőzsér, J., Mótyán, J.A., 2021. Development of a Bio-Layer Interferometry-Based Protease Assay Using HIV-1 Protease as a Model. Viruses 13, 1183. https://doi.org/10.3390/v13061183
125. Milosevits, G., Mészáros, T., Őrfi, E., Bakos, T., Garami, M., Kovács, G., Dézsi, L., Hamar, P., Győrffy, B., Szabó, A., Szénási, G., Szebeni, J., 2021. Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusion. Nanomedicine 34, 102366. https://doi.org/10.1016/j.nano.2021.102366
126. Molnár, B., Sere, P., Bordé, S., Koós, K., Zsigri, N., Horváth, P., Lőrincz, M.L., 2021. Cell Type-Specific Arousal-Dependent Modulation of Thalamic Activity in the Lateral Geniculate Nucleus. Cereb Cortex Commun 2, tgab020. https://doi.org/10.1093/texcom/tgab020
127. Molnár, P.J., Dér, B., Borsodi, K., Balla, H., Borbás, Z., Molnár, K., Ruisanchez, É., Kenessey, I., Horváth, A., Keszthelyi, A., Majoros, A., Nyirády, P., Offermanns, S., Benyó, Z., 2021. Isoprostanes evoke contraction of the murine and human detrusor muscle via activation of the thromboxane prostanoid TP receptor and Rho kinase. Am J Physiol Renal Physiol 320, F537–F547. https://doi.org/10.1152/ajprenal.00400.2020
128. Moreno-Indias, I., Lahti, L., Nedyalkova, M., Elbere, I., Roshchupkin, G., Adilovic, M., Aydemir, O., Bakir-Gungor, B., Santa Pau, E.C., D’Elia, D., Desai, M.S., Falquet, L., Gundogdu, A., Hron, K., Klammsteiner, T., Lopes, M.B., Marcos-Zambrano, L.J., Marques, C., Mason, M., May, P., Pašić, L., Pio, G., Pongor, S., Promponas, V.J., Przymus, P., Saez-Rodriguez, J., Sampri, A., Shigdel, R., Stres, B., Suharoschi, R., Truu, J., Truică, C.-O., Vilne, B., Vlachakis, D., Yilmaz, E., Zeller, G., Zomer, A.L., Gómez-Cabrero, D., Claesson, M.J., 2021. Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions. Front Microbiol 12, 635781. https://doi.org/10.3389/fmicb.2021.635781
129. Mortensen, M.B., Glehen, O., Horvath, P., Hübner, M., Hyung-Ho, K., Königsrainer, A., Pocard, M., Reymond, M.A., So, J., Fristrup, C.W., 2021. The ISSPP PIPAC database: design, process, access, and first interim analysis. Pleura Peritoneum 6, 91–97. https://doi.org/10.1515/pp-2021-0108
130. Mótyán, J.A., Miczi, M., Oroszlan, S., Tőzsér, J., 2021. Specificity of the HIV-1 Protease on Substrates Representing the Cleavage Site in the Proximal Zinc-Finger of HIV-1 Nucleocapsid Protein. Viruses 13, 1092. https://doi.org/10.3390/v13061092
131. Nagy, Á., Győrffy, B., 2021. muTarget: A platform linking gene expression changes and mutation status in solid tumors. Int J Cancer 148, 502–511. https://doi.org/10.1002/ijc.33283
132. Nagy, Á., Ligeti, B., Szebeni, J., Pongor, S., Gyrffy, B., 2021a. COVIDOUTCOME-estimating COVID severity based on mutation signatures in the SARS-CoV-2 genome. Database (Oxford) 2021, baab020. https://doi.org/10.1093/database/baab020
133. Nagy, Á., Munkácsy, G., Győrffy, B., 2021b. Pancancer survival analysis of cancer hallmark genes. Sci Rep 11, 6047. https://doi.org/10.1038/s41598-021-84787-5
134. Nagy, Á., Pongor, S., Győrffy, B., 2021c. Different mutations in SARS-CoV-2 associate with severe and mild outcome. Int J Antimicrob Agents 57, 106272. https://doi.org/10.1016/j.ijantimicag.2020.106272
135. Nagy, N., Dubois, A., Szell, M., Rajan, N., 2021. Genetic Testing in CYLD Cutaneous Syndrome: An Update. Appl Clin Genet 14, 427–444. https://doi.org/10.2147/TACG.S288274
136. Nagy-Baló, Z., Kiss, R., Demeter, J., Bödör, C., Bajtay, Z., Erdei, A., 2021. BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. PLoS One 16, e0254853. https://doi.org/10.1371/journal.pone.0254853
137. Nelhűbel, G.A., Cserepes, M., Szabó, B., Türk, D., Kárpáti, A., Kenessey, I., Rásó, E., Barbai, T., Hegedűs, Z., László, V., Szokol, B., Dobos, J., Őrfi, L., Tóvári, J., 2021. EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas. Pathol Oncol Res 27, 620256. https://doi.org/10.3389/pore.2021.620256
138. Nguyen, C.M., Santoso, C.M.A., Vu, D.T.H., Szőllősi, G., Bata, R., Zsuga, J., Nagy, A.C., 2021. Awareness Related to Cardiometabolic Diseases: A Cross-Sectional Study in Southern Vietnam. Int J Environ Res Public Health 18, 10209. https://doi.org/10.3390/ijerph181910209
139. Olah, C., Hahnen, C., Nagy, N., Musial, J., Varadi, M., Nyiro, G., Gyorffy, B., Hadaschik, B., Rawitzer, J., Ting, S., Sjödahl, G., Hoffmann, M.J., Reis, H., Szarvas, T., 2022. A quantitative polymerase chain reaction based method for molecular subtype classification of urinary bladder cancer-Stromal gene expressions show higher prognostic values than intrinsic tumor genes. Int J Cancer 150, 856–867. https://doi.org/10.1002/ijc.33809
140. Ősz, Á., Lánczky, A., Győrffy, B., 2021. Survival analysis in breast cancer using proteomic data from four independent datasets. Sci Rep 11, 16787. https://doi.org/10.1038/s41598-021-96340-5
141. Oziegbe, E.J., Ocan, O.O., Costin, G., Horváth, P., 2021. Geochemistry and mineral chemistry of pelitic gneiss of Ikare area, southwestern Nigeria. Heliyon 7, e08543. https://doi.org/10.1016/j.heliyon.2021.e08543
142. Pajkos, M., Dosztányi, Z., 2021. Functions of intrinsically disordered proteins through evolutionary lenses. Prog Mol Biol Transl Sci 183, 45–74. https://doi.org/10.1016/bs.pmbts.2021.06.017
143. Pálinkás, H.L., Pongor, L., Balajti, M., Nagy, Á., Nagy, K., Békési, A., Bianchini, G., Vértessy, B.G., Győrffy, B., 2022. Primary Founder Mutations in the PRKDC Gene Increase Tumor Mutation Load in Colorectal Cancer. Int J Mol Sci 23, 633. https://doi.org/10.3390/ijms23020633
144. Palla, G., Pollner, P., Börcsök, J., Major, A., Molnár, B., Csabai, I., 2021. Hierarchy and control of ageing-related methylation networks. PLoS Comput Biol 17, e1009327. https://doi.org/10.1371/journal.pcbi.1009327
145. Panza, S., Malivindi, R., Caruso, A., Russo, U., Giordano, F., Győrffy, B., Gelsomino, L., De Amicis, F., Barone, I., Conforti, F.L., Giordano, C., Bonofiglio, D., Catalano, S., Andò, S., 2021. Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells. Cancers (Basel) 13, 4555. https://doi.org/10.3390/cancers13184555
146. Pápay, Z.E., Magramane, S., Király, M., Szalkai, P., Ludányi, K., Horváth, P., Antal, I., 2021. Optimization and Development of Albumin-Biopolymer Bioconjugates with Solubility-Improving Properties. Biomedicines 9, 737. https://doi.org/10.3390/biomedicines9070737
147. Papp, L.A., Ács-Szabó, L., Batta, G., Miklós, I., 2021a. Molecular and comparative genomic analyses reveal evolutionarily conserved and unique features of the Schizosaccharomyces japonicus mycelial growth and the underlying genomic changes. Curr Genet 67, 953–968. https://doi.org/10.1007/s00294-021-01206-y
148. Papp, L.A., Ács-Szabó, L., Póliska, S., Miklós, I., 2021b. A modified culture medium and hyphae isolation method can increase quality of the RNA extracted from mycelia of a dimorphic fungal species. Curr Genet 67, 823–830. https://doi.org/10.1007/s00294-021-01181-4
149. Pastuszka, A., Beauruelle, C., Camiade, E., Rousseau, G.M., Moineau, S., Mereghetti, L., Horvath, P., Lanotte, P., 2021. Functional Study of the Type II-A CRISPR-Cas System of Streptococcus agalactiae Hypervirulent Strains. CRISPR J 4, 233–242. https://doi.org/10.1089/crispr.2020.0145
150. Pataki, B.A., Garriga, J., Eritja, R., Palmer, J.R.B., Bartumeus, F., Csabai, I., 2021. Deep learning identification for citizen science surveillance of tiger mosquitoes. Sci Rep 11, 4718. https://doi.org/10.1038/s41598-021-83657-4
151. Patthy, L., 2021a. Exon Shuffling Played a Decisive Role in the Evolution of the Genetic Toolkit for the Multicellular Body Plan of Metazoa. Genes (Basel) 12, 382. https://doi.org/10.3390/genes12030382
152. Patthy, L., 2021b. Miguel Llinás and the Structure of the Kringle Fold. Protein J 40, 450–453. https://doi.org/10.1007/s10930-021-09981-w
153. Peirsman, A., Blondeel, E., Ahmed, T., Anckaert, J., Audenaert, D., Boterberg, T., Buzas, K., Carragher, N., Castellani, G., Castro, F., Dangles-Marie, V., Dawson, J., De Tullio, P., De Vlieghere, E., Dedeyne, S., Depypere, H., Diosdi, A., Dmitriev, R.I., Dolznig, H., Fischer, S., Gespach, C., Goossens, V., Heino, J., Hendrix, A., Horvath, P., Kunz-Schughart, L.A., Maes, S., Mangodt, C., Mestdagh, P., Michlíková, S., Oliveira, M.J., Pampaloni, F., Piccinini, F., Pinheiro, C., Rahn, J., Robbins, S.M., Siljamäki, E., Steigemann, P., Sys, G., Takayama, S., Tesei, A., Tulkens, J., Van Waeyenberge, M., Vandesompele, J., Wagemans, G., Weindorfer, C., Yigit, N., Zablowsky, N., Zanoni, M., Blondeel, P., De Wever, O., 2021. MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity. Nat Methods 18, 1294–1303. https://doi.org/10.1038/s41592-021-01291-4
154. Periyasamy, M., Singh, A.K., Gemma, C., Farzan, R., Allsopp, R.C., Shaw, J.A., Charmsaz, S., Young, L.S., Cunnea, P., Coombes, R.C., Győrffy, B., Buluwela, L., Ali, S., 2021. Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB. Oncogene 40, 1077–1090. https://doi.org/10.1038/s41388-020-01583-7
155. Petschner, P., Baksa, D., Hullam, G., Torok, D., Millinghoffer, A., Deakin, J.F.W., Bagdy, G., Juhasz, G., 2021. A replication study separates polymorphisms behind migraine with and without depression. PLoS One 16, e0261477. https://doi.org/10.1371/journal.pone.0261477
156. Piovesan, D., Necci, M., Escobedo, N., Monzon, A.M., Hatos, A., Mičetić, I., Quaglia, F., Paladin, L., Ramasamy, P., Dosztányi, Z., Vranken, W.F., Davey, N.E., Parisi, G., Fuxreiter, M., Tosatto, S.C.E., 2021. MobiDB: intrinsically disordered proteins in 2021. Nucleic Acids Res 49, D361–D367. https://doi.org/10.1093/nar/gkaa1058
157. Potor, L., Hendrik, Z., Patsalos, A., Katona, É., Méhes, G., Póliska, S., Csősz, É., Kalló, G., Komáromi, I., Combi, Z., Posta, N., Sikura, K.É., Pethő, D., Oros, M., Vereb, G., Tóth, C., Gergely, P., Nagy, L., Balla, G., Balla, J., 2021. Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis. Antioxid Redox Signal 35, 917–950. https://doi.org/10.1089/ars.2020.8234
158. Prekovic, S., Schuurman, K., Mayayo-Peralta, I., Manjón, A.G., Buijs, M., Yavuz, S., Wellenstein, M.D., Barrera, A., Monkhorst, K., Huber, A., Morris, B., Lieftink, C., Chalkiadakis, T., Alkan, F., Silva, J., Győrffy, B., Hoekman, L., van den Broek, B., Teunissen, H., Debets, D.O., Severson, T., Jonkers, J., Reddy, T., de Visser, K.E., Faller, W., Beijersbergen, R., Altelaar, M., de Wit, E., Medema, R., Zwart, W., 2021. Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. Nat Commun 12, 4360. https://doi.org/10.1038/s41467-021-24537-3
159. Puskas, R., Bikov, A., Horvath, P., Lazar, Z., Kunos, L., Nagy, R., Pinter, G., Galffy, G., 2021. Circulating Survivin Protein Levels in Lung Cancer Patients Treated With Platinum-Based Chemotherapy. Pathol Oncol Res 27, 631969. https://doi.org/10.3389/pore.2021.631969
160. Rajha, A., Piso, P., Halmy, L., Panczel, I., Nedelcut, D.-S., Herold, Z., Szasz, A.M., Acs, M., 2022. Rare Histologies and Infrequent Indications for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. Anticancer Res 42, 3681–3692. https://doi.org/10.21873/anticanres.15857
161. Reveron-Thornton, R., Scott, B.J., Post, D., Caulfield, A.F., Werbaneth, K., Hovsepian, D.A., Spiegel, J., Miklos, D., Thomas, R.P., Patel, C.B., 2022. Recurrent Status Epilepticus in the Setting of Chimeric Antigen Receptor (CAR)-T Cell Therapy. Neurohospitalist 12, 74–79. https://doi.org/10.1177/19418744211000980
162. Révész, Á., Milley, M.G., Nagy, K., Szabó, D., Kalló, G., Csősz, É., Vékey, K., Drahos, L., 2021. Tailoring to Search Engines: Bottom-Up Proteomics with Collision Energies Optimized for Identification Confidence. J Proteome Res 20, 474–484. https://doi.org/10.1021/acs.jproteome.0c00518
163. Reynolds, C., Kontschán, J., Takács, N., Solymosi, N., Sándor, A.D., Keve, G., Hornok, S., 2022. Shift in the seasonality of ixodid ticks after a warm winter in an urban habitat with notes on morphotypes of Ixodes ricinus and data in support of cryptic species within Ixodes frontalis. Exp Appl Acarol 88, 127–138. https://doi.org/10.1007/s10493-022-00756-1
164. Rojas, K., Baliu-Piqué, M., Manzano, A., Saiz-Ladera, C., García-Barberán, V., Cimas, F.J., Pérez-Segura, P., Pandiella, A., Győrffy, B., Ocana, A., 2021. In silico transcriptomic mapping of integrins and immune activation in Basal-like and HER2+ breast cancer. Cell Oncol (Dordr) 44, 569–580. https://doi.org/10.1007/s13402-020-00583-9
165. Ruksakiet, K., Stercz, B., Tóth, G., Jaikumpun, P., Gróf, I., Tengölics, R., Lohinai, Z.M., Horváth, P., Deli, M.A., Steward, M.C., Dobay, O., Zsembery, Á., 2021. Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa. Biology (Basel) 10, 519. https://doi.org/10.3390/biology10060519
166. Saiz-Ladera, C., Baliu-Piqué, M., Cimas, F.J., Manzano, A., García-Barberán, V., Camarero, S.C., Hinojal, G.F., Pandiella, A., Győrffy, B., Stewart, D., Cruz-Hernández, J.J., Pérez-Segura, P., Ocana, A., 2021. Transcriptomic Correlates of Immunologic Activation in Head and Neck and Cervical Cancer. Front Oncol 11, 714550. https://doi.org/10.3389/fonc.2021.714550
167. Sawicka-Smiarowska, E., Bondarczuk, K., Bauer, W., Niemira, M., Szalkowska, A., Raczkowska, J., Kwasniewski, M., Tarasiuk, E., Dubatowka, M., Lapinska, M., Szpakowicz, M., Stachurska, Z., Szpakowicz, A., Sowa, P., Raczkowski, A., Kondraciuk, M., Gierej, M., Motyka, J., Jamiolkowski, J., Bondarczuk, M., Chlabicz, M., Bucko, J., Kozuch, M., Dobrzycki, S., Bychowski, J., Musial, W.J., Godlewski, A., Ciborowski, M., Gyenesei, A., Kretowski, A., Kaminski, K.A., 2021. Gut Microbiome in Chronic Coronary Syndrome Patients. J Clin Med 10, 5074. https://doi.org/10.3390/jcm10215074
168. Schläpfer, M., Dong, L., O’Keeffe, K., Santi, P., Szell, M., Salat, H., Anklesaria, S., Vazifeh, M., Ratti, C., West, G.B., 2021. The universal visitation law of human mobility. Nature 593, 522–527. https://doi.org/10.1038/s41586-021-03480-9
169. Schvarcz, C.A., Danics, L., Krenács, T., Viana, P., Béres, R., Vancsik, T., Nagy, Á., Gyenesei, A., Kun, J., Fonović, M., Vidmar, R., Benyó, Z., Kaucsár, T., Hamar, P., 2021. Modulated Electro-Hyperthermia Induces a Prominent Local Stress Response and Growth Inhibition in Mouse Breast Cancer Isografts. Cancers (Basel) 13, 1744. https://doi.org/10.3390/cancers13071744
170. Sebestyén, E., Nagy, Á., Marosvári, D., Rajnai, H., Kajtár, B., Deák, B., Matolcsy, A., Brandner, S., Storhoff, J., Chen, N., Bagó, A.G., Bödör, C., Reiniger, L., 2022. Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas. J Mol Diagn 24, 224–240. https://doi.org/10.1016/j.jmoldx.2021.11.005
171. Shafran, J.S., Jafari, N., Casey, A.N., Győrffy, B., Denis, G.V., 2021. BRD4 regulates key transcription factors that drive epithelial-mesenchymal transition in castration-resistant prostate cancer. Prostate Cancer Prostatic Dis 24, 268–277. https://doi.org/10.1038/s41391-020-0246-y
172. Shahvaran, S.A., Menyhárt, O., Csedrik, L., Patai, Á.V., 2021. Diagnosis and Prevalence of Cirrhotic Cardiomyopathy: A Systematic Review and Meta-analysis. Curr Probl Cardiol 46, 100821. https://doi.org/10.1016/j.cpcardiol.2021.100821
173. Siddharth, S., Parida, S., Muniraj, N., Hercules, S., Lim, D., Nagalingam, A., Wang, C., Gyorffy, B., Daniel, J.M., Sharma, D., 2021. Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression. Elife 10, e70729. https://doi.org/10.7554/eLife.70729
174. Skrapits, K., Sárvári, M., Farkas, I., Göcz, B., Takács, S., Rumpler, É., Váczi, V., Vastagh, C., Rácz, G., Matolcsy, A., Solymosi, N., Póliska, S., Tóth, B., Erdélyi, F., Szabó, G., Culler, M.D., Allet, C., Cotellessa, L., Prévot, V., Giacobini, P., Hrabovszky, E., 2021. The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia. Elife 10, e67714. https://doi.org/10.7554/eLife.67714
175. Steffen, P.A., Altmutter, C., Dworschak, E., Junttila, S., Gyenesei, A., Zhu, X., Kockmann, T., Ringrose, L., 2021. The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival. Chromosoma 130, 215–234. https://doi.org/10.1007/s00412-021-00762-z
176. Stercz, B., Farkas, F.B., Tóth, Á., Gajdács, M., Domokos, J., Horváth, V., Ostorházi, E., Makra, N., Kocsis, B., Juhász, J., Ligeti, B., Pongor, S., Szabó, D., 2021. The influence of antibiotics on transitory resistome during gut colonization with CTX-M-15 and OXA-162 producing Klebsiella pneumoniae ST15. Sci Rep 11, 6335. https://doi.org/10.1038/s41598-021-85766-6
177. Szabo, D., Sarszegi, Z., Polgar, B., Saghy, E., Nemeth, A., Reglodi, D., Makkos, A., Gorbe, A., Helyes, Z., Ferdinandy, P., Herczeg, R., Gyenesei, A., Cziraki, A., Tamas, A., 2021. PACAP-38 in Acute ST-Segment Elevation Myocardial Infarction in Humans and Pigs: A Translational Study. Int J Mol Sci 22, 2883. https://doi.org/10.3390/ijms22062883
178. Szabó, J., Maróti, G., Solymosi, N., Andrásofszky, E., Tuboly, T., Bersényi, A., Bruckner, G., Hullár, I., 2021. Fructose, glucose and fat interrelationships with metabolic pathway regulation and effects on the gut microbiota. Acta Vet Hung 69, 134–156. https://doi.org/10.1556/004.2021.00022
179. Szabó, Z.-I., Orbán, G., Borbás, E., Csicsák, D., Kádár, S., Fiser, B., Dobó, M., Horváth, P., Kiss, E., Budai, L., Dobos, J., Pálla, T., Őrfi, L., Völgyi, G., Tóth, G., 2021. Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility. Heliyon 7, e07581. https://doi.org/10.1016/j.heliyon.2021.e07581
180. Szabolcsi, Z., Demeter, A., Kiraly, P., Balogh, A., Wilson, M.L., King, J.R., Hetey, S., Gelencser, Z., Matsuo, K., Hargitai, B., Mhawech-Fauceglia, P., Hupuczi, P., Szilagyi, A., Papp, Z., Roman, L.D., Cortessis, V.K., Than, N.G., 2021. Epigenetic Dysregulation of Trophoblastic Gene Expression in Gestational Trophoblastic Disease. Biomedicines 9, 1935. https://doi.org/10.3390/biomedicines9121935
181. Szadai, L., Velasquez, E., Szeitz, B., Almeida, N.P. de, Domont, G., Betancourt, L.H., Gil, J., Marko-Varga, M., Oskolas, H., Jánosi, Á.J., Boyano-Adánez, M.D.C., Kemény, L., Baldetorp, B., Malm, J., Horvatovich, P., Szász, A.M., Németh, I.B., Marko-Varga, G., 2021. Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out. Cancers (Basel) 13, 6105. https://doi.org/10.3390/cancers13236105
182. Szatmári, L., Cserkész, T., Laczkó, L., Lanszki, J., Pertoldi, C., Abramov, A.V., Elmeros, M., Ottlecz, B., Hegyeli, Z., Sramkó, G., 2021. A comparison of microsatellites and genome-wide SNPs for the detection of admixture brings the first molecular evidence for hybridization between Mustela eversmanii and M. putorius (Mustelidae, Carnivora). Evol Appl 14, 2286–2304. https://doi.org/10.1111/eva.13291
183. Szkalisity, A., Piccinini, F., Beleon, A., Balassa, T., Varga, I.G., Migh, E., Molnar, C., Paavolainen, L., Timonen, S., Banerjee, I., Ikonen, E., Yamauchi, Y., Ando, I., Peltonen, J., Pietiäinen, V., Honti, V., Horvath, P., 2021. Regression plane concept for analysing continuous cellular processes with machine learning. Nat Commun 12, 2532. https://doi.org/10.1038/s41467-021-22866-x
184. Tahkola, K., Ahtiainen, M., Kellokumpu, I., Mecklin, J.-P., Laukkarinen, J., Laakkonen, J., Kenessey, I., Jalkanen, S., Salmi, M., Böhm, J., 2021. Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer. Virchows Arch 478, 209–217. https://doi.org/10.1007/s00428-020-02888-4
185. Tálas, A., Huszár, K., Kulcsár, P.I., Varga, J.K., Varga, É., Tóth, E., Welker, Z., Erdős, G., Pach, P.F., Welker, Á., Györgypál, Z., Tusnády, G.E., Welker, E., 2021. A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs. Nucleic Acids Res 49, e31. https://doi.org/10.1093/nar/gkaa1220
186. Tamás, A., Tóth, D., Pham, D., Loibl, C., Rendeki, S., Csontos, C., Rozanovic, M., Bogár, L., Polgár, B., Németh, J., Gyenesei, A., Herczeg, R., Szántó, Z., Reglődi, D., 2021. Changes of pituitary adenylate cyclase activating polypeptide (PACAP) level in polytrauma patients in the early post-traumatic period. Peptides 146, 170645. https://doi.org/10.1016/j.peptides.2021.170645
187. Tar, I., Csősz, É., Végh, E., Lundberg, K., Kharlamova, N., Soós, B., Szekanecz, Z., Márton, I., 2021. Salivary citrullinated proteins in rheumatoid arthritis and associated periodontal disease. Sci Rep 11, 13525. https://doi.org/10.1038/s41598-021-93008-y
188. Tarca, A.L., Pataki, B.Á., Romero, R., Sirota, M., Guan, Y., Kutum, R., Gomez-Lopez, N., Done, B., Bhatti, G., Yu, T., Andreoletti, G., Chaiworapongsa, T., DREAM Preterm Birth Prediction Challenge Consortium, Hassan, S.S., Hsu, C.-D., Aghaeepour, N., Stolovitzky, G., Csabai, I., Costello, J.C., 2021. Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth. Cell Rep Med 2, 100323. https://doi.org/10.1016/j.xcrm.2021.100323
189. Tarca, A.L., Taran, A., Romero, R., Jung, E., Paredes, C., Bhatti, G., Ghita, C., Chaiworapongsa, T., Than, N.G., Hsu, C.-D., 2022. Prediction of preeclampsia throughout gestation with maternal characteristics and biophysical and biochemical markers: a longitudinal study. Am J Obstet Gynecol 226, 126.e1-126.e22. https://doi.org/10.1016/j.ajog.2021.01.020
190. Thell, R., Kallab, V., Weinhappel, W., Mueckstein, W., Heschl, L., Heschl, M., Korsatko, S., Toedling, F., Blaschke, A., Herzog, T., Klicpera, A., Koeller, C., Haugk, M., Kreil, A., Spiel, A., Kreuzer, P., Krause, R., Sebesta, C., Winkler, S., Laky, B., Szell, M., 2021. Evaluation of a novel, rapid antigen detection test for the diagnosis of SARS-CoV-2. PLoS One 16, e0259527. https://doi.org/10.1371/journal.pone.0259527
191. Tompa, M., Kajtar, B., Galik, B., Gyenesei, A., Kalman, B., 2021. DNA methylation and protein expression of Wnt pathway markers in progressive glioblastoma. Pathol Res Pract 222, 153429. https://doi.org/10.1016/j.prp.2021.153429
192. Tóth, A.G., Csabai, I., Judge, M.F., Maróti, G., Becsei, Á., Spisák, S., Solymosi, N., 2021. Mobile Antimicrobial Resistance Genes in Probiotics. Antibiotics (Basel) 10, 1287. https://doi.org/10.3390/antibiotics10111287
193. Tóth, A.G., Tóth, I., Rózsa, B., Dubecz, A., Patai, Á.V., Németh, T., Kaplan, S., Kovács, E.G., Makrai, L., Solymosi, N., 2022. Canine Saliva as a Possible Source of Antimicrobial Resistance Genes. Antibiotics (Basel) 11, 1490. https://doi.org/10.3390/antibiotics11111490
194. Toth, L., Czigler, A., Horvath, P., Kornyei, B., Szarka, N., Schwarcz, A., Ungvari, Z., Buki, A., Toth, P., 2021a. Traumatic brain injury-induced cerebral microbleeds in the elderly. Geroscience 43, 125–136. https://doi.org/10.1007/s11357-020-00280-3
195. Toth, L., Czigler, A., Horvath, P., Szarka, N., Kornyei, B., Toth, A., Schwarcz, A., Ungvari, Z., Buki, A., Toth, P., 2021b. The Effect of Mild Traumatic Brain Injury on Cerebral Microbleeds in Aging. Front Aging Neurosci 13, 717391. https://doi.org/10.3389/fnagi.2021.717391
196. Überrück, L., Nadiradze, G., Yurttas, C., Königsrainer, A., Königsrainer, I., Horvath, P., 2021. In-Hospital Mortality and Complication Rates According to Health Insurance Data in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies in Germany. Ann Surg Oncol 28, 3823–3830. https://doi.org/10.1245/s10434-020-09301-z
197. Ujma, P.P., Eszlári, N., Millinghoffer, A., Bruncsics, B., Török, D., Petschner, P., Antal, P., Deakin, B., Breen, G., Bagdy, G., Juhász, G., 2022. Genetic effects on educational attainment in Hungary. Brain Behav 12, e2430. https://doi.org/10.1002/brb3.2430
198. Vadovics, M., Ho, J., Igaz, N., Alföldi, R., Rakk, D., Veres, É., Szücs, B., Horváth, M., Tóth, R., Szücs, A., Csibi, A., Horváth, P., Tiszlavicz, L., Vágvölgyi, C., Nosanchuk, J.D., Szekeres, A., Kiricsi, M., Henley-Smith, R., Moyes, D.L., Thavaraj, S., Brown, R., Puskás, L.G., Naglik, J.R., Gácser, A., 2021. Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo. mBio 13, e0314421. https://doi.org/10.1128/mBio.03144-21
199. Vokó, Z., Kiss, Z., Surján, G., Surján, O., Barcza, Z., Pályi, B., Formanek-Balku, E., Molnár, G.A., Herczeg, R., Gyenesei, A., Miseta, A., Kollár, L., Wittmann, I., Müller, C., Kásler, M., 2022a. Nationwide effectiveness of five SARS-CoV-2 vaccines in Hungary-the HUN-VE study. Clin Microbiol Infect 28, 398–404. https://doi.org/10.1016/j.cmi.2021.11.011
200. Vokó, Z., Kiss, Z., Surján, G., Surján, O., Barcza, Z., Wittmann, I., Molnár, G.A., Nagy, D., Müller, V., Bogos, K., Nagy, P., Kenessey, I., Wéber, A., Polivka, L., Pálosi, M., Szlávik, J., Rokszin, G., Müller, C., Szekanecz, Z., Kásler, M., 2022b. Effectiveness and Waning of Protection With Different SARS-CoV-2 Primary and Booster Vaccines During the Delta Pandemic Wave in 2021 in Hungary (HUN-VE 3 Study). Front Immunol 13, 919408. https://doi.org/10.3389/fimmu.2022.919408
201. Walker, P.J., Siddell, S.G., Lefkowitz, E.J., Mushegian, A.R., Adriaenssens, E.M., Alfenas-Zerbini, P., Davison, A.J., Dempsey, D.M., Dutilh, B.E., García, M.L., Harrach, B., Harrison, R.L., Hendrickson, R.C., Junglen, S., Knowles, N.J., Krupovic, M., Kuhn, J.H., Lambert, A.J., Łobocka, M., Nibert, M.L., Oksanen, H.M., Orton, R.J., Robertson, D.L., Rubino, L., Sabanadzovic, S., Simmonds, P., Smith, D.B., Suzuki, N., Van Dooerslaer, K., Vandamme, A.-M., Varsani, A., Zerbini, F.M., 2021. Changes to virus taxonomy and to the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2021). Arch Virol 166, 2633–2648. https://doi.org/10.1007/s00705-021-05156-1
202. Yurttas, C., Horvath, P., Fischer, I., Meisner, C., Nadalin, S., Königsrainer, I., Königsrainer, A., Beckert, S., Löffler, M.W., 2021. A Prospective, Phase I/II, Open-Label Pilot Trial to Assess the Safety of Hyperthermic Intraperitoneal Chemotherapy After Oncological Resection of Pancreatic Adenocarcinoma. Ann Surg Oncol 28, 9086–9095. https://doi.org/10.1245/s10434-021-10187-8
203. Yurttas, C., Thiel, C., Wichmann, D., Horvath, P., Strohäker, J., Bongers, M.N., Schenk, M., Stüker, D., Königsrainer, A., Thiel, K., 2022a. Retrospective analysis of different therapeutic approaches for retroperitoneal duodenal perforations. Sci Rep 12, 10243. https://doi.org/10.1038/s41598-022-14278-8
204. Yurttas, C., Überrück, L., Nadiradze, G., Königsrainer, A., Horvath, P., 2022b. Limitations of laparoscopy to assess the peritoneal cancer index and eligibility for cytoreductive surgery with HIPEC in peritoneal metastasis. Langenbecks Arch Surg 407, 1667–1675. https://doi.org/10.1007/s00423-022-02455-2
205. Zeke, A., Dobson, L., Szekeres, L.I., Langó, T., Tusnády, G.E., 2021. PolarProtDb: A Database of Transmembrane and Secreted Proteins showing Apical-Basal Polarity. J Mol Biol 433, 166705. https://doi.org/10.1016/j.jmb.2020.11.004
206. Zodanu, G.K.E., Oszlánczi, M., Havasi, K., Kalapos, A., Rácz, G., Katona, M., Ujfalusi, A., Nagy, O., Széll, M., Nagy, D., 2021. Systemic Screening for 22q11.2 Copy Number Variations in Hungarian Pediatric and Adult Patients With Congenital Heart Diseases Identified Rare Pathogenic Patterns in the Region. Front Genet 12, 635480. https://doi.org/10.3389/fgene.2021.635480
207. Zsebők, S., Herczeg, G., Laczi, M., Nagy, G., Vaskuti, É., Hargitai, R., Hegyi, G., Herényi, M., Markó, G., Rosivall, B., Szász, E., Szöllősi, E., Török, J., Garamszegi, L.Z., 2021. Sequential organization of birdsong: relationships with individual quality and fitness. Behav Ecol 32, 82–93. https://doi.org/10.1093/beheco/araa104
208. Zsigrai, S., Kalmár, A., Barták, B.K., Nagy, Z.B., Szigeti, K.A., Valcz, G., Kothalawala, W., Dankó, T., Sebestyén, A., Barna, G., Pipek, O., Csabai, I., Tulassay, Z., Igaz, P., Takács, I., Molnár, B., 2022. Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines. Cancers (Basel) 14, 1820. https://doi.org/10.3390/cancers14071820